Uh-Hyun Kim
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Explore the profile of Uh-Hyun Kim including associated specialties, affiliations and a list of published articles.
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73
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1277
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Recent Articles
1.
Mushtaq M, Mahmood M, Jabbar U, Kim U
Bioimpacts
. 2024 Mar;
14(2):27780.
PMID: 38505670
Introduction: CD38 is a multifunctional enzyme with a potent Ca mobilizing effect, cyclic ADP-ribose (cADPR), and nicotinic acid adenine dinucleotide phosphate (NAADP). Here, we aimed to demonstrate the role of...
2.
Rah S, Joe Y, Park J, Ryter S, Park C, Chung H, et al.
Exp Mol Med
. 2023 Jul;
55(7):1492-1505.
PMID: 37394593
Hepatic glucose production by glucagon is crucial for glucose homeostasis during fasting, yet the underlying mechanisms remain incompletely delineated. Although CD38 has been detected in the nucleus, its function in...
3.
Park J, Rah S, An H, Lee J, Roh G, Ryter S, et al.
Metabolism
. 2023 Feb;
141:155516.
PMID: 36773805
Objective: Emerging evidence suggests that crosstalk between Kupffer cells (KCs) and hepatocytes protects against non-alcoholic fatty liver disease (NAFLD). However, the underlying mechanisms that lead to the reduction of steatosis...
4.
Kim U
Cell Calcium
. 2022 Feb;
103:102562.
PMID: 35219154
Since the discovery of the pyridine nucleotide metabolites Ca mobilizing messengers cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP), they have been demonstrated to function as Ca signaling...
5.
Do M, Park J, Chen Y, Rah S, Nghiem T, Gong J, et al.
Aging (Albany NY)
. 2022 Feb;
14(3):1233-1252.
PMID: 35166693
The protein kinase R (PKR)-like endoplasmic reticulum (ER) kinase (PERK), a key ER stress sensor of the unfolded protein response (UPR), can confer beneficial effects by facilitating the removal of...
6.
Gul R, Kim U, Alfadda A
Eur J Pharmacol
. 2020 Oct;
890:173656.
PMID: 33086029
Angiotensin-converting enzyme 2 (ACE2) has been recognized as a potential entry receptor for SARS-CoV-2 infection. Binding of SARS-CoV-2 to ACE2 allows engagement with pulmonary epithelial cells and pulmonary infection with...
7.
Nam T, Park D, Rah S, Woo T, Chung H, Brenner C, et al.
FASEB J
. 2020 Jul;
34(9):12565-12576.
PMID: 32717131
Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most potent Ca mobilizing second messenger whose formation has remained elusive. In vitro, CD38-mediated NAADP synthesis requires an acidic pH and a...
8.
Song H, Chen Y, Chen Y, Park J, Zheng M, Surh Y, et al.
Free Radic Res
. 2020 Jul;
54(11-12):918-930.
PMID: 32623920
The translocation of transcription factor EB (TFEB) to the nucleus plays a pivotal role in the regulation of basic cellular processes, such as lysosome biogenesis and autophagy. Autophagy is an...
9.
Park J, Kim J, Chen Y, Song H, Chen Y, Zheng M, et al.
Free Radic Res
. 2020 Apr;
54(11-12):848-858.
PMID: 32228197
Oxidative stress is recognised as a key factor that can lead to cellular senescence and aging. Carbon monoxide (CO) is produced by haemoxygenase-1 (HO-1), which exerts cytoprotective effects in aging-related...
10.
Joe Y, Chen Y, Park J, Kim H, Rah S, Ryu J, et al.
Cell Rep
. 2020 Jan;
30(4):1063-1076.e5.
PMID: 31995750
The resolution phase of acute inflammation is essential for tissue homeostasis, yet the underlying mechanisms remain unclear. We demonstrate that resolution of inflammation involves interactions between CD38 and tristetraprolin (TTP)....