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Uditi Bhatt

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Articles 5
Citations 17
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Recent Articles
1.
King J, Chen K, Evans C, Norret M, Almasri R, Pavlos N, et al.
Chem Sci . 2024 Sep; PMID: 39246363
Antisense oligonucleotides (ASOs) are a well-established therapeutic modality based on RNA interference, but low cellular uptake, limited ability to direct ASO trafficking, and a range of intracellular barriers to successful...
2.
Lawler N, Bhatt U, Agarwal V, Evans C, Kaluskar P, Amos S, et al.
Adv Healthc Mater . 2024 Sep; 13(32):e2400364. PMID: 39221662
Central nervous system (CNS) injuries and neurodegenerative diseases have markedly poor prognoses and can result in permanent dysfunction due to the general inability of CNS neurons to regenerate. Differentiation of...
3.
Bhatt U, Cucchiarini A, Luo Y, Evans C, Mergny J, Iyer K, et al.
Genome Res . 2024 Feb; 34(2):217-230. PMID: 38355305
Secondary structure is a principal determinant of lncRNA function, predominantly regarding scaffold formation and interfaces with target molecules. Noncanonical secondary structures that form in nucleic acids have known roles in...
4.
Bhatt U, Kretzmann A, Guedin A, Ou A, Kobelke S, Bond C, et al.
Biochimie . 2021 Jul; 190:124-131. PMID: 34329720
Paraspeckles are RNA-protein structures within the nucleus of mammalian cells, capable of orchestrating various biochemical processes. An overexpression of the architectural component of paraspeckles, a long non-coding RNA called NEAT1...
5.
Toshniwal P, Nguyen M, Guedin A, Viola H, Ho D, Kim Y, et al.
FEBS Lett . 2019 Nov; 593(22):3149-3161. PMID: 31677274
Scar formation after wound healing is a major medical problem. A better understanding of the dynamic nuclear architecture of the genome during wound healing could provide insights into the underlying...