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Udaya Pratap Singh

Explore the profile of Udaya Pratap Singh including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 121
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Recent Articles
1.
Patowary P, Shakya A, Ghosh S, Jamir L, Sahariah B, Gogoi N, et al.
Chem Biodivers . 2025 Feb; :e202401524. PMID: 39903847
In this study, a structurally directed pharmacophore hybridization technique is used to combine the two essential structural scaffolds coumarin and thiazoles in search of a new class of acetylcholinesterase (AChE)...
2.
Devanath B, Chetia B, Shakya A, Ghosh S, Patgiri S, Bhowmick I, et al.
3 Biotech . 2024 Nov; 14(12):301. PMID: 39554985
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-024-04129-w.
3.
Islam M, Pathak K, Saikia R, Pramanik P, Das A, Talukdar P, et al.
Arch Pharm (Weinheim) . 2024 Aug; 357(11):e2400307. PMID: 39106224
Coronavirus disease 2019 (COVID-19) the most contagious infection caused by the unique type of coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), produced a global pandemic that wreaked...
4.
Borgohain P, Shakya A, Ghosh S, Gogoi N, Patgiri S, Bhowmick I, et al.
Exp Parasitol . 2024 Apr; 261:108767. PMID: 38679125
Objectives: Malaria is a significant global health challenge, particularly in Africa, Asia, and Latin America, necessitating immediate investigation into innovative and efficacious treatments. This work involves the development of pyrazole...
5.
Kalita T, Choudhury A, Shakya A, Ghosh S, Singh U, Bhat H
Curr Drug Discov Technol . 2024 Jan; 21(5):e240124226141. PMID: 38279721
Background: Thiazole is a widely studied core structure in heterocyclic chemistry and has proven to be a valuable scaffold in medicinal chemistry. The presence of thiazole in both naturally occurring...
6.
Ali F, Alom S, Ali S, Kondoli B, Sadhu P, Borah C, et al.
Mini Rev Med Chem . 2023 Sep; 24(12):1203-1225. PMID: 37711004
Ebselen is a selenoorganic chiral compound with antioxidant properties comparable to glutathione peroxidase. It is also known as 2-phenyl-1,2-benzisoselenazol-3(2H)-one. In studies examining its numerous pharmacological activities, including antioxidant, anticancer, antiviral,...
7.
Gupta A, Bhat H, Singh U
RSC Med Chem . 2023 Aug; 14(8):1512-1536. PMID: 37593577
Novel 1,3,5-triazine derivatives bearing oxazine have been synthesized and tested for their ability to inhibit a panel of dipeptidyl peptidase (DPP)-4, 8, and 9 enzymes. In a comparative inhibitory assay,...
8.
Gupta A, Bhat H, Singh U
Future Med Chem . 2023 Jun; 15(10):829-852. PMID: 37307171
To develop imeglimin-inspired novel 1,3,5-triazine derivatives as antidiabetic agents. These derivatives were synthesized and tested against DPP enzymes. Compound was tested for antidiabetic activity in streptozotocin-induced diabetes in Wistar rats...
9.
Saha A, Choudhury A, Adhikari N, Ghosh S, Shakya A, Patgiri S, et al.
Exp Parasitol . 2023 May; 250:108546. PMID: 37196703
Objectives: Drug resistance in malaria parasites necessitates the development of new antimalarial drugs with unique mechanisms of action. In the present research work, the PABA conjugated 1,3,5-triazine derivatives were designed...
10.
Saha A, Choudhury A, Adhikari N, Ghosh S, Shakya A, Patgiri S, et al.
J Biomol Struct Dyn . 2023 May; 41(24):15520-15534. PMID: 37154740
In this study, a structurally guided pharmacophore hybridization strategy is used to combine the two key structural scaffolds, -aminobenzoic acid (PABA), and 1,3,5 triazine in search of new series of...