Alpha 2.0
Login Register
» Authors » Uchini S Kosgodage

Uchini S Kosgodage

Explore the profile of Uchini S Kosgodage including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 345
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Chemistry
Top 10 Co-Authors
Sigrun Lange
Jameel M Inal
Igor Kraev
Alistair V Nunn
Geoffrey W Guy
Jimmy D Bell
Nicholas P Chatterton
Paul Matewele
Brigitte Awamaria
Giulia Mastroianni
Published In
Int J Mol Sci
Front Cell Infect Microbiol
Front Pharmacol
Transl Oncol
Affiliations
Soon will be listed here.
Recent Articles
1.
Cannabidiol Is a Novel Modulator of Bacterial Membrane Vesicles
Kosgodage U, Matewele P, Awamaria B, Kraev I, Warde P, Mastroianni G, et al.
Front Cell Infect Microbiol . 2019 Sep; 9:324. PMID: 31552202
Membrane vesicles (MVs) released from bacteria participate in cell communication and host-pathogen interactions. Roles for MVs in antibiotic resistance are gaining increased attention and in this study we investigated if...
2.
Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitize Bacteria to Antibiotic Treatment
Kosgodage U, Matewele P, Mastroianni G, Kraev I, Brotherton D, Awamaria B, et al.
Front Cell Infect Microbiol . 2019 Jul; 9:227. PMID: 31316918
Outer membrane and membrane vesicles (OMV/MV) are released from bacteria and participate in cell communication, biofilm formation and host-pathogen interactions. Peptidylarginine deiminases (PADs) are phylogenetically conserved enzymes that catalyze post-translational...
3.
Peptidylarginine Deiminases Post-Translationally Deiminate Prohibitin and Modulate Extracellular Vesicle Release and MicroRNAs in Glioblastoma Multiforme
Kosgodage U, Uysal-Onganer P, Maclatchy A, Kraev I, Chatterton N, Nicholas A, et al.
Int J Mol Sci . 2019 Jan; 20(1). PMID: 30597867
Glioblastoma multiforme (GBM) is the most aggressive form of adult primary malignant brain tumour with poor prognosis. Extracellular vesicles (EVs) are a key-mediator through which GBM cells promote a pro-oncogenic...
4.
Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells
Kosgodage U, Uysal-Onganer P, Maclatchy A, Mould R, Nunn A, Guy G, et al.
Transl Oncol . 2019 Jan; 12(3):513-522. PMID: 30597288
Glioblastoma multiforme (GBM) is the most common and aggressive form of primary malignant brain tumor in adults, with poor prognosis. Extracellular vesicles (EVs) are key-mediators for cellular communication through transfer...
5.
Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer
Kosgodage U, Mould R, Henley A, Nunn A, Guy G, Thomas E, et al.
Front Pharmacol . 2018 Aug; 9:889. PMID: 30150937
Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells and involved in intercellular communication through transfer of proteins and genetic material. EMV release is also associated with various...
6.
Peptidylarginine Deiminases-Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?
Lange S, Gallagher M, Kholia S, Kosgodage U, Hristova M, Hardy J, et al.
Int J Mol Sci . 2017 Jun; 18(6). PMID: 28587234
Exosomes and microvesicles (EMVs) are lipid bilayer-enclosed structures released from cells and participate in cell-to-cell communication via transport of biological molecules. EMVs play important roles in various pathologies, including cancer...
7.
Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy
Kosgodage U, Trindade R, Thompson P, Inal J, Lange S
Int J Mol Sci . 2017 May; 18(5). PMID: 28486412
Microvesicle (MV) release from tumour cells influences drug retention, contributing to cancer drug resistance. Strategically regulating MV release may increase drug retention within cancer cells and allow for lower doses...