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Geoffrey W Guy

Explore the profile of Geoffrey W Guy including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 701
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Recent Articles
1.
Mould R, Kalampouka I, Thomas E, Guy G, Nunn A, Bell J
Front Physiol . 2023 Oct; 14:1268075. PMID: 37811497
A wide variety of studies have reported some form of non-chemical or non-aqueous communication between physically isolated organisms, eliciting changes in cellular proliferation, morphology, and/or metabolism. The sources and mechanisms...
2.
Nunn A, Guy G, Bell J
Int J Mol Sci . 2023 Sep; 24(17). PMID: 37685877
Before the late 1980s, ideas around how the lipophilic phytocannabinoids might be working involved membranes and bioenergetics as these disciplines were "in vogue". However, as interest in genetics and pharmacology...
3.
Nunn A, Guy G, Bell J
Bioelectricity . 2023 Jan; 4(4):237-247. PMID: 36636557
The consensus on the origins of life is that it involved organization of prebiotic chemicals according to the underlying principles of thermodynamics to dissipate energy derived from photochemical and/or geochemical...
4.
Nunn A, Guy G, Brysch W, Bell J
Biomedicines . 2022 Dec; 10(12). PMID: 36551869
Many people infected with the SARS-CoV-2 suffer long-term symptoms, such as "brain fog", fatigue and clotting problems. Explanations for "long COVID" include immune imbalance, incomplete viral clearance and potentially, mitochondrial...
5.
Hodges R, Chase K, Tripson M, Bingham S, Woolley-Roberts M, Guy G, et al.
Cannabis Cannabinoid Res . 2022 Sep; 8(5):790-801. PMID: 36125410
There are few vocal learning animals that are suitable for laboratory study, and so songbirds have unique utility for evaluating drug effects on behavior learned during a critical period of...
6.
Nunn A, Guy G, Botchway S, Bell J
Immun Ageing . 2021 Oct; 18(1):40. PMID: 34717676
We, and others, have suggested that as the SARS-CoV-2 virus may modulate mitochondrial function, good mitochondrial reserve and health could be key in determining disease severity when exposed to this...
7.
Mould R, Botchway S, Parkinson J, Thomas E, Guy G, Bell J, et al.
Front Mol Biosci . 2021 May; 8:630107. PMID: 34046425
The cannabinoid, cannabidiol (CBD), is part of the plant's natural defense system that when given to animals has many useful medicinal properties, including activity against cancer cells, modulation of the...
8.
Sahuri-Arisoylu M, Mould R, Shinjyo N, Bligh S, Nunn A, Guy G, et al.
Front Nutr . 2021 May; 8:588466. PMID: 33937302
Acetate is one of the main short chain fatty acids produced in the colon when fermentable carbohydrates are digested. It has been shown to affect normal metabolism, modulating mitochondrial function,...
9.
Nunn A, Guy G, Brysch W, Botchway S, Frasch W, Calabrese E, et al.
Immun Ageing . 2020 Dec; 17(1):33. PMID: 33292333
Infection with SARs-COV-2 displays increasing fatality with age and underlying co-morbidity, in particular, with markers of the metabolic syndrome and diabetes, which seems to be associated with a "cytokine storm"...
10.
Beiersdorf J, Hevesi Z, Calvigioni D, Pyszkowski J, Romanov R, Szodorai E, et al.
JCI Insight . 2020 Nov; 5(23). PMID: 33141759
Ongoing societal changes in views on the medical and recreational roles of cannabis increased the use of concentrated plant extracts with a Δ9-tetrahydrocannabinol (THC) content of more than 90%. Even...