U Hemmann
Overview
Explore the profile of U Hemmann including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
426
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Recent Articles
1.
Lovell D, Fellows M, Saul J, Whitwell J, Custer L, Dertinger S, et al.
Mutat Res Genet Toxicol Environ Mutagen
. 2020 Feb;
849:503086.
PMID: 32087845
A database of micronuclei counts for historical negative control data from rat in vivo micronuclei tests performed in 10 different laboratories was established. Data were available from over 4000 negative...
2.
Damm K, Hemmann U, Garin-Chesa P, Hauel N, Kauffmann I, Priepke H, et al.
EMBO J
. 2001 Dec;
20(24):6958-68.
PMID: 11742973
Telomerase, the ribonucleoprotein enzyme maintaining the telomeres of eukaryotic chromosomes, is active in most human cancers and in germline cells but, with few exceptions, not in normal human somatic tissues....
3.
Haan S, Hemmann U, Hassiepen U, Schaper F, Schneider-Mergener J, Wollmer A, et al.
J Biol Chem
. 1999 Jan;
274(3):1342-8.
PMID: 9880505
Signal transducers and activators of transcription (STATs) are important mediators of cytokine signal transduction. STAT factors are recruited to phosphotyrosine-containing motifs of activated receptor chains via their SH2 domains. The...
4.
Muller-Newen G, Kuster A, Hemmann U, Keul R, Horsten U, Martens A, et al.
J Immunol
. 1998 Dec;
161(11):6347-55.
PMID: 9834125
Soluble receptors for several cytokines have been detected in body fluids and are believed to modulate the cytokine response by binding the ligand and thereby reducing its bioavailability. In the...
5.
Korolenko T, Heinrich P, Hemmann U, Weiergraber O, Dittrich E, Graeve L
Biull Eksp Biol Med
. 1998 Feb;
124(11):527-9.
PMID: 9471247
No abstract available.
6.
Sasse J, Hemmann U, Schwartz C, Schniertshauer U, Heesel B, Landgraf C, et al.
Mol Cell Biol
. 1997 Aug;
17(8):4677-86.
PMID: 9234724
Signal transducer and transcription (STAT) factors are activated by tyrosine phosphorylation in response to a variety of cytokines, growth factors, and hormones. Tyrosine phosphorylation triggers dimerization and nuclear translocation of...
7.
Graeve L, Korolenko T, Hemmann U, Weiergraber O, Dittrich E, Heinrich P
FEBS Lett
. 1996 Dec;
399(1-2):131-4.
PMID: 8980136
In human body fluids a soluble form of the interleukin-6 receptor (sIL-6R) has been found which together with interleukin-6 (IL-6) acts agonistically on cells expressing the signal transducer gp130. The...
8.
Will A, Hemmann U, Horn F, Rollinghoff M, Gessner A
J Immunol
. 1996 Nov;
157(10):4576-83.
PMID: 8906836
IFN-gamma is a pleiotropic cytokine that plays a major role in anti-infectious immune responses. The physiologic effects of IFN-gamma are thought to be mediated by the binding of extracellular IFN-gamma...
9.
Hemmann U, Gerhartz C, Heesel B, Sasse J, Kurapkat G, Grotzinger J, et al.
J Biol Chem
. 1996 May;
271(22):12999-3007.
PMID: 8662795
Distinct yet overlapping sets of STAT transcription factors are activated by different cytokines. One example is the differential activation of acute phase response factor (APRF, also called Stat3) and Stat1...
10.
Gerhartz C, Heesel B, Sasse J, Hemmann U, Landgraf C, Schneider-Mergener J, et al.
J Biol Chem
. 1996 May;
271(22):12991-8.
PMID: 8662591
Interleukin-6 (IL-6) and gamma-interferon (IFNgamma) activate an overlapping set of genes via the Jak/STAT pathway. However, at least in human cells, a differential activation of STAT transcription factors was observed:...