Tyler Mrozowich
Overview
Explore the profile of Tyler Mrozowich including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
164
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mrozowich T, Park S, Waldl M, Henrickson A, Tersteeg S, Nelson C, et al.
Nucleic Acids Res
. 2023 Mar;
51(9):4588-4601.
PMID: 36999609
Numerous viruses utilize essential long-range RNA-RNA genome interactions, specifically flaviviruses. Using Japanese encephalitis virus (JEV) as a model system, we computationally predicted and then biophysically validated and characterized its long-range...
2.
Tersteeg S, Mrozowich T, Henrickson A, Demeler B, Patel T
Biochem Cell Biol
. 2022 Aug;
100(5):425-436.
PMID: 35926232
Inorganic pyrophosphatase (iPPase) is an enzyme that cleaves pyrophosphate into two phosphate molecules. This enzyme is an essential component of in vitro transcription (IVT) reactions for RNA preparation as it...
3.
DSouza M, Mrozowich T, Badmalia M, Geeraert M, Frederickson A, Henrickson A, et al.
Nucleic Acids Res
. 2022 May;
50(10):5881-5898.
PMID: 35639511
Human Long Intergenic Noncoding RNA-p21 (LincRNA-p21) is a regulatory noncoding RNA that plays an important role in promoting apoptosis. LincRNA-p21 is also critical in down-regulating many p53 target genes through...
4.
Aguilar R, Spencer K, Kesner B, Rizvi N, Badmalia M, Mrozowich T, et al.
Nature
. 2022 Mar;
604(7904):160-166.
PMID: 35355011
Although more than 98% of the human genome is non-coding, nearly all of the drugs on the market target one of about 700 disease-related proteins. The historical reluctance to invest...
5.
Meier-Stephenson V, Badmalia M, Mrozowich T, Lau K, Schultz S, Gemmill D, et al.
J Biol Chem
. 2021 Mar;
296:100589.
PMID: 33774051
Approximately 250 million people worldwide are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing cirrhosis and hepatocellular carcinoma. The HBV genome persists as...
6.
Nelson C, Mrozowich T, Gemmill D, Park S, Patel T
Int J Mol Sci
. 2021 Jan;
22(1).
PMID: 33401776
Flavivirus genus includes many deadly viruses such as the Japanese encephalitis virus (JEV) and Zika virus (ZIKV). The 5' terminal regions (TR) of flaviviruses interact with human proteins and such...
7.
Nelson C, Mrozowich T, Park S, Dsouza S, Henrickson A, Vigar J, et al.
Int J Mol Sci
. 2020 Dec;
22(1).
PMID: 33374561
Rift Valley fever virus (RVFV) is a mosquito-transmitted virus from the family that causes high rates of mortality and morbidity in humans and ruminant animals. Previous studies indicated that DEAD-box...
8.
Badmalia M, Siddiqui M, Mrozowich T, Gemmill D, Patel T
Eur Biophys J
. 2020 Oct;
49(8):809-818.
PMID: 33067686
Analytical ultracentrifugation (AUC) has emerged as a robust and reliable technique for biomolecular characterization with extraordinary sensitivity. AUC is widely used to study purity, conformational changes, biomolecular interactions, and stoichiometry....
9.
Mrozowich T, Henrickson A, Demeler B, Patel T
Viruses
. 2020 Feb;
12(2).
PMID: 32046304
Viral infections are responsible for numerous deaths worldwide. Flaviviruses, which contain RNA as their genetic material, are one of the most pathogenic families of viruses. There is an increasing amount...
10.
Kim D, Thiel B, Mrozowich T, Hennelly S, Hofacker I, Patel T, et al.
Nat Commun
. 2020 Jan;
11(1):148.
PMID: 31919376
Long non-coding RNAs (lncRNAs) constitute a significant fraction of the transcriptome, playing important roles in development and disease. However, our understanding of structure-function relationships for this emerging class of RNAs...