Tyler Matheny
Overview
Explore the profile of Tyler Matheny including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
1317
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Matheny T, Van Treeck B, Huynh T, Parker R
RNA
. 2023 Oct;
29(11):1837.
PMID: 37845045
No abstract available.
2.
Campbell A, Dyle M, Albanese R, Matheny T, Sudheendran K, Cortazar M, et al.
Cell Rep
. 2023 Jun;
42(6):112642.
PMID: 37314931
Nonsense-mediated RNA decay (NMD) degrades transcripts carrying premature termination codons. NMD is thought to prevent the synthesis of toxic truncated proteins. However, whether loss of NMD results in widespread production...
3.
Diaz A, Matheny T, Stephenson D, Nemkov T, DAlessandro A, Reis T
bioRxiv
. 2023 Feb;
PMID: 36824729
Metabolism in males and females is distinct. Differences are usually linked to sexual reproduction, with circulating signals (e.g. hormones) playing major roles. By contrast, sex differences prior to sexual maturity...
4.
Khong A, Matheny T, Huynh T, Babl V, Parker R
Nat Commun
. 2022 Jun;
13(1):3735.
PMID: 35768440
The presence of the mA modification in mammalian mRNAs is proposed to promote mRNA recruitment to stress granules through the interaction with YTHDF proteins. We test this possibility by examining...
5.
Carvill G, Matheny T, Hesselberth J, Demarest S
Neurotherapeutics
. 2021 Oct;
18(3):1500-1514.
PMID: 34648141
This review summarizes the pathogenic mechanisms that underpin the monogenic epilepsies and discusses the potential of novel precision therapeutics to treat these disorders. Pathogenic mechanisms of epilepsy include recessive (null...
6.
Matheny T, Van Treeck B, Huynh T, Parker R
RNA
. 2020 Nov;
27(2):174-189.
PMID: 33199441
Stress granules (SGs) are stress-induced RNA-protein assemblies formed from a complex transcriptome of untranslating ribonucleoproteins (RNPs). Although RNAs can be either enriched or depleted from SGs, the rules that dictate...
7.
Matheny T, Rao B, Parker R
Mol Cell Biol
. 2019 Oct;
39(24).
PMID: 31591142
The eukaryotic cytosol contains multiple RNP granules, including P-bodies and stress granules. Three different methods have been used to describe the transcriptome of stress granules or P-bodies, but how these...
8.
Burke J, Moon S, Matheny T, Parker R
Mol Cell
. 2019 Sep;
75(6):1203-1217.e5.
PMID: 31494035
In response to foreign and endogenous double-stranded RNA (dsRNA), protein kinase R (PKR) and ribonuclease L (RNase L) reprogram translation in mammalian cells. PKR inhibits translation initiation through eIF2α phosphorylation,...
9.
Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al.
Hum Mol Genet
. 2019 Feb;
28(13):2143-2160.
PMID: 30806671
Aberrant translational repression is a feature of multiple neurodegenerative diseases. The association between disease-linked proteins and stress granules further implicates impaired stress responses in neurodegeneration. However, our knowledge of the...
10.
Van Treeck B, Protter D, Matheny T, Khong A, Link C, Parker R
Proc Natl Acad Sci U S A
. 2018 Feb;
115(11):2734-2739.
PMID: 29483269
Stress granules are higher order assemblies of nontranslating mRNAs and proteins that form when translation initiation is inhibited. Stress granules are thought to form by protein-protein interactions of RNA-binding proteins....