Tung-Liang Chung
Overview
Explore the profile of Tung-Liang Chung including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
355
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Recent Articles
1.
OBrien C, Chy H, Zhou Q, Blumenfeld S, Lambshead J, Liu X, et al.
Stem Cells
. 2016 Dec;
35(3):626-640.
PMID: 28009074
The study and application of human pluripotent stem cells (hPSCs) will be enhanced by the availability of well-characterized monoclonal antibodies (mAbs) detecting cell-surface epitopes. Here, we report generation of seven...
2.
Tian W, Wang Y, Xu Y, Guo X, Wang B, Sun L, et al.
J Biol Chem
. 2013 Dec;
289(6):3339-51.
PMID: 24371136
Megadose vitamin C (Vc) is one of the most enduring alternative treatments for diverse human diseases and is deeply engrafted in popular culture. Preliminary studies in the 1970s described potent...
3.
Briggs J, Sun J, Shepherd J, Ovchinnikov D, Chung T, Nayler S, et al.
Stem Cells
. 2012 Dec;
31(3):467-78.
PMID: 23225669
Down syndrome (DS) is the most frequent cause of human congenital mental retardation. Cognitive deficits in DS result from perturbations of normal cellular processes both during development and in adult...
4.
Chung T, Turner J, Thaker N, Kolle G, Cooper-White J, Grimmond S, et al.
Stem Cells
. 2010 Aug;
28(10):1782-93.
PMID: 20715184
Human embryonic stem cells (hESCs) and induced pluripotent stem cells have the ability to adapt to various culture conditions. Phenotypic and epigenetic changes brought about by the culture conditions can,...
5.
Chung T, Brena R, Kolle G, Grimmond S, Berman B, Laird P, et al.
Stem Cells
. 2010 Aug;
28(10):1848-55.
PMID: 20687155
Vitamin C (ascorbate) is a widely used medium supplement in embryonic stem cell culture. Here, we show that ascorbate causes widespread, consistent, and remarkably specific DNA demethylation of 1,847 genes...
6.
Prowse A, Doran M, Cooper-White J, Chong F, Munro T, Fitzpatrick J, et al.
Biomaterials
. 2010 Aug;
31(32):8281-8.
PMID: 20674971
Human embryonic stem cells (hESC) are expected to provide revolutionary therapeutic applications and drug discovery technologies. In order for this to be achieved a reproducible, defined animal component free culture...
7.
Li S, Liu Y, Tseng C, Chung T, Lee T, Singh S
Stem Cells Dev
. 2006 Sep;
15(4):532-55.
PMID: 16978057
Many human embryonic stem cell (hESC) lines have been reported, but only a few of them have been fully characterized. In this report, five new hESC lines were derived from...
8.
Herszfeld D, Wolvetang E, Langton-Bunker E, Chung T, Filipczyk A, Houssami S, et al.
Nat Biotechnol
. 2006 Feb;
24(3):351-7.
PMID: 16501577
The application of human embryonic stem (hES) cells in regenerative medicine will require rigorous quality control measures to ensure the safety of hES cell-derived grafts. During propagation in vitro, hES...
9.
Chung T, Hsiao H, Yeh Y, Shia H, Chen Y, Liang P, et al.
J Biol Chem
. 2004 Jul;
279(38):39653-62.
PMID: 15272016
Protein sumoylation by small ubiquitin-like modifier (SUMO) proteins is an important post-translational regulatory modification. A role in the control of chromosome dynamics was first suggested when SUMO was identified as...