Tung-Chang Liu
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Explore the profile of Tung-Chang Liu including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
46
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Recent Articles
1.
Huang K, Wu C, Toh S, Liu T, Tu C, Lin Y, et al.
Nucleic Acids Res
. 2023 Oct;
51(21):11927-11940.
PMID: 37870446
In various autoimmune diseases, dysfunctional TREX1 (Three prime Repair Exonuclease 1) leads to accumulation of endogenous single-stranded DNA (ssDNA), double-stranded DNA (dsDNA) and DNA/RNA hybrids in the cytoplasm and triggers...
2.
Liu T, Guo K, Chu J, Hsiao Y
Comput Struct Biotechnol J
. 2021 Jul;
19:3682-3691.
PMID: 34285771
Mammalian apurinic/apyrimidinic (AP) endonuclease 1 (APE1) has versatile enzymatic functions, including redox, endonuclease, and exonuclease activities. APE1 is thus broadly associated with pathways in DNA repair, cancer cell growth, and...
3.
Liu T, Lin C, Chang K, Guo K, Wang S, Chu J, et al.
Nat Commun
. 2021 Jan;
12(1):601.
PMID: 33504804
The exonuclease activity of Apurinic/apyrimidinic endonuclease 1 (APE1) is responsible for processing matched/mismatched terminus in various DNA repair pathways and for removing nucleoside analogs associated with drug resistance. To fill...
4.
Huang K, Liu T, Liang R, Chu L, Cheng H, Chu J, et al.
PLoS Biol
. 2018 May;
16(5):e2005653.
PMID: 29734329
Three prime repair exonuclease 1 (TREX1) is an essential exonuclease in mammalian cells, and numerous in vivo and in vitro data evidenced its participation in immunity regulation and in genotoxicity...