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Tsutomu Nakada

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Articles 163
Citations 1986
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Recent Articles
1.
Fukiage Y, Low S, Muramoto A, Ariga Y, Hoshino H, Nakada T, et al.
J Histochem Cytochem . 2025 Mar; 73(1-2):55-61. PMID: 40026103
Glycoprotein 2 (GP2), initially identified as a primary membrane protein of zymogen granules in pancreatic acinar cells, is a marker of intestinal microfold cells (M cells) and involved in bacterial...
2.
Tanaka Y, Kadota S, Zhao J, Kobayashi H, Okano S, Izumi M, et al.
Stem Cell Res Ther . 2023 Sep; 14(1):240. PMID: 37679796
Background: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can be used to treat heart diseases; however, the optimal maturity of hiPSC-CMs for effective regenerative medicine remains unclear. We aimed to...
3.
Murayama T, Kurebayashi N, Numaga-Tomita T, Kobayashi T, Okazaki S, Yamashiro K, et al.
J Gen Physiol . 2022 Nov; 154(12). PMID: 36318155
In skeletal muscle excitation-contraction (E-C) coupling, depolarization of the plasma membrane triggers Ca2+ release from the sarcoplasmic reticulum (SR), referred to as depolarization-induced Ca2+ release (DICR). DICR occurs through the...
4.
Ariga Y, Low S, Hoshino H, Nakada T, Akama T, Muramoto A, et al.
J Histochem Cytochem . 2022 Sep; 70(10):683-694. PMID: 36169277
Spi-B, a member of the E26 transformation-specific (ETS) family of transcription factors, plays an important role in B cell differentiation. Spi-B also functions in development of diffuse large B-cell lymphoma;...
5.
Kawagishi H, Nakada T, Numaga-Tomita T, Larranaga M, Guo A, Song L, et al.
Am J Physiol Heart Circ Physiol . 2022 May; 323(1):H103-H120. PMID: 35594067
Mammalian ventricular cardiomyocytes are premature at birth and exhibit substantial phenotypic changes before weaning. Mouse ventricular myocytes undergo cell division several times after birth; however, the regulatory mechanisms and roles...
6.
Nakada T, Yamada M
Nihon Yakurigaku Zasshi . 2022 Jan; 157(1):4-8. PMID: 34980811
Striated muscle L-type calcium channels (LTCC) are localized specifically to the junctional membrane (JM) where the sarcolemma is closely apposed to the sarcoplasmic reticulum. Although this allocation of LTCC is...
7.
Inazumi H, Kuwahara K, Nakagawa Y, Kuwabara Y, Numaga-Tomita T, Kashihara T, et al.
Circ Res . 2021 Dec; 130(2):234-248. PMID: 34875852
Background: During the development of heart failure, a fetal cardiac gene program is reactivated and accelerates pathological cardiac remodeling. We previously reported that a transcriptional repressor, NRSF (neuron restrictive silencer...
8.
Natsumeda M, Igarashi H, Gabdulkhaev R, Takahashi H, Motohashi K, Ogura R, et al.
Diagnostics (Basel) . 2021 Nov; 11(11). PMID: 34829476
We have previously published a study on the reliable detection of 2-hydroxyglutarate (2HG) in lower-grade gliomas by magnetic resonance spectroscopy (MRS). In this short article, we re-evaluated five glioma cases...
9.
Cui N, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, et al.
Endocrinology . 2021 Feb; 162(3). PMID: 33545715
Adrenomedullin (AM) is a peptide hormone with multiple physiological functions, which are regulated by its receptor activity-modifying proteins, RAMP2 and RAMP3. We previously reported that AM or RAMP2 knockout (KO)...
10.
Kashihara T, Kawagishi H, Nakada T, Numaga-Tomita T, Kadota S, Wolf E, et al.
JACC Basic Transl Sci . 2020 Dec; 5(11):1057-1069. PMID: 33294739
The treatment of pediatric heart failure is a long-standing unmet medical need. Angiotensin II supports mammalian perinatal circulation by activating cardiac L-type Ca channels through angiotensin type 1 receptor (ATR)...