Truyen Nguyen
Overview
Explore the profile of Truyen Nguyen including associated specialties, affiliations and a list of published articles.
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14
Citations
2862
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Recent Articles
1.
Samadpour M, Benoit L, Myoda S, Hans B, Nadala C, Kim S, et al.
Appl Environ Microbiol
. 2024 Jul;
90(7):e0070024.
PMID: 38953659
Importance: is an opportunistic pathogen that can cause significant morbidity and mortality in neonates. Its transmission dynamics are poorly understood, though powered infant formula (PIF) is thought to be the...
2.
Monroe J, Tanis K, Podtelezhnikov A, Nguyen T, Machotka S, Lynch D, et al.
Toxicol Sci
. 2020 Jun;
177(1):281-299.
PMID: 32559301
Drug-induced liver injury is a major reason for drug candidate attrition from development, denied commercialization, market withdrawal, and restricted prescribing of pharmaceuticals. The metabolic bioactivation of drugs to chemically reactive...
3.
Butora G, Qi N, Fu W, Nguyen T, Huang H, Davies I
Angew Chem Int Ed Engl
. 2014 Oct;
53(51):14046-50.
PMID: 25346363
The cytosolic conversion of therapeutically relevant nucleosides into bioactive triphosphates is often hampered by the inefficiency of the first kinase-mediated step. Nucleoside monophosphate prodrugs can be used to bypass this...
4.
Miksch R, Leek J, Myoda S, Nguyen T, Tenney K, Svidenko V, et al.
J Food Prot
. 2013 Oct;
76(10):1668-75.
PMID: 24112565
Three major outbreaks of salmonellosis linked to consumption of peanut butter during the last 6 years have underscored the need to investigate the potential sources of Salmonella contamination in the...
5.
Nguyen T, Nioi P, Pickett C
J Biol Chem
. 2009 Feb;
284(20):13291-5.
PMID: 19182219
A major mechanism in the cellular defense against oxidative or electrophilic stress is activation of the Nrf2-antioxidant response element signaling pathway, which controls the expression of genes whose protein products...
6.
Nioi P, Nguyen T
Biochem Biophys Res Commun
. 2007 Sep;
362(4):816-21.
PMID: 17822677
Keap1 is the substrate recognition module of a Cullin 3-based E3 ubiquitin ligase. Its primary role is to catalyze the ubiquitylation of the Nrf2 transcription factor. Oxidative stress blocks the...
7.
Nioi P, Nguyen T, Sherratt P, Pickett C
Mol Cell Biol
. 2005 Nov;
25(24):10895-906.
PMID: 16314513
Nrf2 is a transcription factor critical for the maintenance of cellular redox homeostasis. We have previously found that Nrf2 is a labile protein, and its activation in cells under stress...
8.
Nguyen T, Sherratt P, Nioi P, Yang C, Pickett C
J Biol Chem
. 2005 Jul;
280(37):32485-92.
PMID: 16000310
Nrf2 regulates the expression of genes encoding antioxidant proteins involved in cellular redox homeostasis. Previous studies have suggested that activation of Nrf2 is mediated by mechanisms promoting its dissociation from...
9.
Nguyen T, Yang C, Pickett C
Free Radic Biol Med
. 2004 Jul;
37(4):433-41.
PMID: 15256215
The induction of many antioxidant and phase II drug-metabolizing enzymes by phenolic antioxidants and electrophilic compounds is regulated at the transcriptional level. The response to these compounds is mediated by...
10.
Sherratt P, Huang H, Nguyen T, Pickett C
Methods Enzymol
. 2004 Mar;
378:286-301.
PMID: 15038976
No abstract available.