Troy C Sarich
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Explore the profile of Troy C Sarich including associated specialties, affiliations and a list of published articles.
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25
Citations
221
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Recent Articles
1.
Baca-Motes K, Edwards A, Waalen J, Edmonds S, Mehta R, Ariniello L, et al.
Contemp Clin Trials Commun
. 2019 Jan;
14:100318.
PMID: 30656241
Objectives: The advent of large databases, wearable technology, and novel communications methods has the potential to expand the pool of candidate research participants and offer them the flexibility and convenience...
2.
Steinhubl S, Mehta R, Ebner G, Ballesteros M, Waalen J, Steinberg G, et al.
Am Heart J
. 2016 May;
175:77-85.
PMID: 27179726
Efficient methods for screening populations for undiagnosed atrial fibrillation (AF) are needed to reduce its associated mortality, morbidity, and costs. The use of digital technologies, including wearable sensors and large...
3.
Moore K, Krook M, Vaidyanathan S, Sarich T, Damaraju C, Fields L
Clin Pharmacol Drug Dev
. 2016 Apr;
3(4):321-7.
PMID: 27128839
Purpose: Because some patients have difficulty swallowing a whole tablet, we investigated the relative bioavailability of a crushed 20 mg rivaroxaban tablet and of 2 alternative crushed tablet dosing strategies....
4.
Sarich T, Seltzer J, Berkowitz S, Costin J, Curnutte J, Gibson C, et al.
Am Heart J
. 2015 Jun;
169(6):751-7.
PMID: 26027611
This white paper provides a summary of presentations and discussions that were held at an Anticoagulant-Induced Bleeding and Reversal Agents Think Tank co-sponsored by the Cardiac Safety Research Consortium and...
5.
Sarich T, Peters G, Berkowitz S, Misselwitz F, Nessel C, Burton P, et al.
Ann N Y Acad Sci
. 2013 May;
1291:42-55.
PMID: 23701516
The development of rivaroxaban (XARELTO®) is an important new medical advance in the field of oral anticoagulation. Thrombosis-mediated conditions constitute a major burden for patients, healthcare systems, and society. For...
6.
Sarich T, Connelly M, Schranz D, Ghosh A, Manitpisitkul P, Leary E, et al.
Int J Clin Pharmacol Ther
. 2012 May;
50(8):584-94.
PMID: 22578199
Objective: To assess and validate the application of a non-radioactive assay for cholesteryl ester transfer protein (CETP) activity in clinical samples. Design And Methods: In this Phase 0 study, CETP...
7.
Connelly M, Parry T, Giardino E, Huang Z, Cheung W, Chen C, et al.
J Cardiovasc Pharmacol
. 2010 Jan;
55(5):459-68.
PMID: 20051879
Objective: Torcetrapib, a prototype cholesteryl ester transfer protein (CETP) inhibitor with potential for decreasing atherosclerotic disease, increased cardiovascular events in clinical trials. The identified hypertensive and aldosterone-elevating actions of torcetrapib...
8.
Dorani H, Schutzer K, Sarich T, Wall U, Logren U, Ohlsson L, et al.
Eur J Clin Pharmacol
. 2007 Mar;
63(6):571-81.
PMID: 17387462
Objective: To study the effects of amoxicillin, doxycycline, ciprofloxacin, azithromycin, and cefuroxime on the pharmacokinetics and pharmacodynamics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, which...
9.
Wahlander K, Eriksson-Lepkowska M, Nystrom P, Eriksson U, Sarich T, Badimon J, et al.
Thromb Haemost
. 2006 Mar;
95(3):447-53.
PMID: 16525572
It was the objective of this study to compare the antithrombotic effects and bleeding profiles of the oral direct thrombin inhibitor ximelagatran, an anticoagulant, and the antiplatelet agent clopidogrel on...
10.
Eriksson U, Dorani H, Karlsson J, Fritsch H, Hoffmann K, Olsson L, et al.
Drug Metab Dispos
. 2006 Feb;
34(5):775-82.
PMID: 16455803
A pharmacokinetic interaction between erythromycin and ximelagatran, an oral direct thrombin inhibitor, was demonstrated in this study in healthy volunteers. To investigate possible interaction mechanisms, the effects of erythromycin on...