Troy A A Harkness
Overview
Explore the profile of Troy A A Harkness including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
293
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Arnason T, MacDonald-Dickinson V, Gaunt M, Davies G, Lobanova L, Trost B, et al.
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077749
Like humans, canine lymphomas are treated by chemotherapy cocktails and frequently develop multiple drug resistance (MDR). Their shortened clinical timelines and tumor accessibility make canines excellent models to study MDR...
2.
Moradi-Fard S, Mojumdar A, Chan M, Harkness T, Cobb J
Aging Cell
. 2021 May;
20(6):e13373.
PMID: 33979898
The ribosomal DNA (rDNA) in Saccharomyces cerevisiae is in one tandem repeat array on Chromosome XII. Two regions within each repetitive element, called intergenic spacer 1 (IGS1) and IGS2, are...
3.
Khawaja A, Belak Z, Eskiw C, Harkness T
Methods Mol Biol
. 2020 Sep;
2196:229-233.
PMID: 32889725
The budding yeast is a valuable model system for discovering molecular mechanisms underlying cellular aging. This is due to the ease of performing genetic manipulations in yeast and the vast...
4.
Almendariz-Palacios C, Gillespie Z, Janzen M, Martinez V, Bridger J, Harkness T, et al.
Biomedicines
. 2020 Jul;
8(7).
PMID: 32630170
Cellular health is reliant on proteostasis-the maintenance of protein levels regulated through multiple pathways modulating protein synthesis, degradation and clearance. Loss of proteostasis results in serious disease and is associated...
5.
Harkness T
Int J Mol Sci
. 2018 Jun;
19(7).
PMID: 29954095
In aging cells, genomic instability is now recognized as a hallmark event. Throughout life, cells encounter multiple endogenous and exogenous DNA damaging events that are mostly repaired, but inevitably DNA...
6.
Malo M, Postnikoff S, Arnason T, Harkness T
Aging (Albany NY)
. 2016 Apr;
8(4):810-30.
PMID: 27099939
The Saccharomyces cerevisiae Forkhead Box (Fox) orthologs, Forkheads (Fkh) 1 and 2, are conserved transcription factors required for stress response, cell cycle progression and longevity. These yeast proteins play a...
7.
Ghavidel A, Baxi K, Ignatchenko V, Prusinkiewicz M, Arnason T, Kislinger T, et al.
PLoS Genet
. 2015 Aug;
11(8):e1005429.
PMID: 26247883
Proliferating eukaryotic cells undergo a finite number of cell divisions before irreversibly exiting mitosis. Yet pathways that normally limit the number of cell divisions remain poorly characterized. Here we describe...
8.
9.
Postnikoff S, Harkness T
Methods Mol Biol
. 2014 May;
1163:223-7.
PMID: 24841311
Life-span assays in yeast are invaluable in characterizing the functions of gene products on cellular aging. Replicative life-span (RLS) is a measure of the number of divisions an individual cell...
10.
Davies G, Berg A, Postnikoff S, Wilson H, Arnason T, Kusalik A, et al.
PLoS One
. 2014 Feb;
9(1):e84611.
PMID: 24489651
Thrombin and hypoxia are important players in breast cancer progression. Breast cancers often develop drug resistance, but mechanisms linking thrombin and hypoxia to drug resistance remain unresolved. Our studies using...