Trond Myhrer
Overview
Explore the profile of Trond Myhrer including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
294
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Recent Articles
1.
Myhrer T, Mariussen E, Aas P
Neurotoxicology
. 2018 Feb;
65:144-165.
PMID: 29454886
Nerve agent-induced seizures can cause varying degrees of neuropathology depending on level of poisoning and duration of seizing. The intention of this review was to validate a novel approach for...
2.
Myhrer T, Enger S, Aas P
Toxicol Rep
. 2017 Oct;
1:102-113.
PMID: 28962231
Four medical therapies previously shown to exert varying degrees of protection against a convulsant dose of soman were assessed for potential behavioral side effects in a novelty test. In Experiment...
3.
Myhrer T, Aas P
Neurosci Biobehav Rev
. 2016 Nov;
71:657-670.
PMID: 27773692
The threat of chemical warfare agents like nerve agents requires life saving measures of medical pretreatment combined with treatment after exposure. Pretreatment (pyridostigmine) may cause some side effects in a...
4.
Myhrer T, Mariussen E, Enger S, Aas P
Neurotoxicology
. 2015 Aug;
50:142-8.
PMID: 26318504
A treatment regimen consisting of HI-6, levetiracetam, and procyclidine (termed the triple regimen) has previously been shown to work as a universal therapy against soman poisoning in rats, since it...
5.
Myhrer T, Aas P
Neurotoxicology
. 2014 May;
44:27-38.
PMID: 24820435
During the establishment of a research branch, all relevant matters encountered will be of interest to study. After having acquired a body of basal knowledge, it becomes possible to derive...
6.
Myhrer T, Mariussen E, Enger S, Aas P
Eur J Pharmacol
. 2013 Sep;
718(1-3):253-60.
PMID: 24021536
Current treatment of nerve agent poisoning with ionotropic drugs proves inadequate, and alternative treatment strategies are searched for. Based on positive findings with metabotropic glutamate modulators in microinfusion studies, the...
7.
Myhrer T, Enger S, Mariussen E, Aas P
Toxicology
. 2013 Aug;
314(2-3):221-8.
PMID: 23959147
A treatment regimen consisting of HI-6, scopolamine, and physostigmine (termed the physostigmine regimen) has been based on the serendipitous discovery that it exerts powerful antidotal effects against high levels of...
8.
Myhrer T, Enger S, Aas P
Neurotoxicology
. 2012 Nov;
34:128-34.
PMID: 23164931
Microinfusion of anticonvulsants into the perirhinal cortex through 1 guide cannula in each hemisphere only invades a small area of this seizure controlling site in rats exposed to soman. The...
9.
Myhrer T, Enger S, Aas P
Drug Test Anal
. 2012 Sep;
5(8):693-701.
PMID: 22977014
More effective countermeasures against nerve-agent poisoning are needed, because current ones do not protect sufficiently, particularly the central nervous system (CNS). The purpose of the present study was to make...
10.
Myhrer T, Enger S, Jonassen M, Aas P
Neurotoxicology
. 2011 May;
32(6):923-30.
PMID: 21570999
Results from studies based on microinfusions into seizure controlling brain sites (area tempestas, medial septum, perirhinal cortex, posterior piriform cortex) have shown that procyclidine, muscimol, caramiphen, and NBQX, but not...