Trivikram Rajkhowa
Overview
Explore the profile of Trivikram Rajkhowa including associated specialties, affiliations and a list of published articles.
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20
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Recent Articles
11.
Galanis A, Ma H, Rajkhowa T, Ramachandran A, Small D, Cortes J, et al.
Blood
. 2013 Nov;
123(1):94-100.
PMID: 24227820
Mutations of the type III receptor tyrosine kinase FLT3 occur in approximately 30% of acute myeloid leukemia patients and lead to constitutive activation. This has made FLT3-activating mutations an attractive...
12.
Ravandi F, Alattar M, Grunwald M, Rudek M, Rajkhowa T, Richie M, et al.
Blood
. 2013 Apr;
121(23):4655-62.
PMID: 23613521
Patients received 5-azacytidine (AZA) 75 mg/m(2) intravenously daily for 7 days and sorafenib 400 mg orally twice daily continuously; cycles were repeated at ~1-month intervals. Forty-three acute myeloid leukemia (AML)...
13.
Sexauer A, Perl A, Yang X, Borowitz M, Gocke C, Rajkhowa T, et al.
Blood
. 2012 Sep;
120(20):4205-14.
PMID: 23012328
A hallmark of cancer is the disruption of differentiation within tumor cells. Internal tandem duplication mutations of the FLT3 kinase (FLT3/ITD) occur commonly in acute myeloid leukemia (AML) and are...
14.
Fathi A, Arowojolu O, Swinnen I, Sato T, Rajkhowa T, Small D, et al.
Leuk Res
. 2011 Aug;
36(2):224-31.
PMID: 21802138
Patients with acute myeloid leukemia (AML) and a FLT3 internal tandem duplication (ITD) mutation have a poor prognosis, and FLT3 inhibitors are now under clinical investigation. PIM1, a serine/threonine kinase,...
15.
Herman M, Rajkhowa T, Cutuli F, Springate J, Taub M
Am J Physiol Renal Physiol
. 2010 Feb;
298(5):F1222-34.
PMID: 20130120
Prostaglandins (PGs) play a number of roles in the kidney, including regulation of salt and water reabsorption. In this report, evidence was obtained for stimulatory effects of PGs on Na-K-ATPase...
16.
Pratz K, Sato T, Murphy K, Stine A, Rajkhowa T, Levis M
Blood
. 2009 Dec;
115(7):1425-32.
PMID: 20007803
We examined 6 different FMS-like tyrosine kinase-3 (FLT3) inhibitors (lestaurtinib, midostaurin, AC220, KW-2449, sorafenib, and sunitinib) for potency against mutant and wild-type FLT3, as well as for cytotoxic effect against...
17.
Borsick M, Rajkhowa T, Taub M
Biochem Biophys Res Commun
. 2006 May;
345(2):739-45.
PMID: 16701566
The stimulatory effect of PGE1 on the activity of the Na,K-ATPase in MDCK cells is associated with an increase in the rate of transcription of the Na,K-ATPase beta1 subunit gene...
18.
Matlhagela K, Borsick M, Rajkhowa T, Taub M
J Biol Chem
. 2004 Oct;
280(1):334-46.
PMID: 15485816
The Na,K-ATPase is a transmembrane protein responsible for maintaining electrochemical gradients across the plasma membrane in all mammalian cells, a process that is subject to regulation at the transcriptional as...
19.
Taub M, Borsick M, Geisel J, Matlhagela K, Rajkhowa T, Allen C
Exp Cell Res
. 2004 Aug;
299(1):1-14.
PMID: 15302568
Prostaglandins (PGs) play a significant role in the regulation of sodium reabsorption by the kidney, in addition to accumulating during inflammation as well as in several solid tumors. Previously, we...
20.
Taub M, Han H, Rajkhowa T, Allen C, Park J
Exp Cell Res
. 2002 Dec;
281(2):205-12.
PMID: 12460651
Primary rabbit kidney proximal tubule (RPT) cells (S.D. Chung et al., 1982, J. Cell Biol. 95, 118-126) were transfected with the vector pRSV-T, which contains SV40 early region genes. After...