Trine Pagh Ludvigsen
Overview
Explore the profile of Trine Pagh Ludvigsen including associated specialties, affiliations and a list of published articles.
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10
Citations
71
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Recent Articles
1.
Christoffersen B, Kristensen C, Lindgaard R, Kirk R, Viuff B, Kvist P, et al.
Sci Rep
. 2023 Apr;
13(1):6017.
PMID: 37045950
Obesity-related glomerulopathy and diabetic nephropathy (DN) are serious complications to metabolic syndrome and diabetes. The purpose was to study effects of a fat, fructose and cholesterol-rich (FFC) diet with and...
2.
Drag M, Debes K, Franck C, Flethoj M, Lyhne M, Moller J, et al.
Epigenetics
. 2023 Apr;
18(1):2199374.
PMID: 37032646
Profiling of circulating cell-free DNA (cfDNA) by tissue-specific base modifications, such as 5-methylcytosines (5mC), may enable the monitoring of ongoing pathophysiological processes. Nanopore sequencing allows genome-wide 5mC detection in cfDNA...
3.
Bentsen S, Clemmensen A, Loft M, Flethoj M, Debes K, Ludvigsen T, et al.
Diagnostics (Basel)
. 2021 Oct;
11(10).
PMID: 34679505
Angiogenesis is crucial in tissue repair and prevents scar tissue formation following an ischemic event such as myocardial infarction. The ischemia induces formation of new capillaries, which have high expression...
4.
Pedersen K, Gradel A, Ludvigsen T, Christoffersen B, Fuglsang-Damgaard C, Bendtsen K, et al.
Transl Res
. 2021 Aug;
239:71-84.
PMID: 34428585
Prediction of human pharmacokinetics (PK) from data obtained in animal studies is essential in drug development. Here, we present a thorough examination of how to achieve good pharmacokinetic data from...
5.
Christiansen L, Dohlmann T, Ludvigsen T, Parfieniuk E, Ciborowski M, Szczerbinski L, et al.
Sci Rep
. 2021 Jan;
11(1):2167.
PMID: 33500513
Statins lower the risk of cardiovascular events but have been associated with mitochondrial functional changes in a tissue-dependent manner. We investigated tissue-specific modifications of mitochondrial function in liver, heart and...
6.
Cirera S, Tasoz E, Jacobsen M, Schumacher-Petersen C, Christoffersen B, Kirk R, et al.
Nutr Diabetes
. 2020 Mar;
10(1):9.
PMID: 32205840
Background: Model animals are valuable resources for dissecting basic aspects of the regulation of obesity and metabolism. The translatability of results relies on understanding comparative aspects of molecular pathophysiology. Several...
7.
Ludvigsen T, Olsen L, Pedersen H, Christoffersen B, Jensen L
Clin Sci (Lond)
. 2019 Dec;
133(24):2499-2516.
PMID: 31830262
Obesity and diabetes in humans are associated with hypertrophic remodeling and increased media:lumen ratio of small resistance arteries, which is an independent predictor of cardiovascular events. In order to minimize...
8.
Schumacher-Petersen C, Christoffersen B, Kirk R, Ludvigsen T, Zois N, Pedersen H, et al.
J Transl Med
. 2019 Apr;
17(1):110.
PMID: 30943987
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in humans, and ranges from steatosis to non-alcoholic steatohepatitis (NASH), the latter with risk of progression to cirrhosis....
9.
Andreasen L, Krog S, Ludvigsen T, Nielsen O, Moller J, Christoffersen B, et al.
Nutr Metab (Lond)
. 2018 Sep;
15:64.
PMID: 30263039
Background: Dietary interventions have been shown to attenuate some of the myocardial pathological alterations associated with obesity. This study evaluated the effect of dietary normalization from a fat/fructose/cholesterol-rich diet to...
10.
Ludvigsen T, Kirk R, Christoffersen B, Pedersen H, Martinussen T, Kildegaard J, et al.
J Transl Med
. 2015 Sep;
13:312.
PMID: 26394837
Background: From a pharmacological perspective, readily-available, well-characterized animal models of cardiovascular disease, including relevant in vivo markers of atherosclerosis are important for evaluation of novel drug candidates. Furthermore, considering the...