Trevor S Barlowe
Overview
Explore the profile of Trevor S Barlowe including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
299
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0
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Recent Articles
11.
Barlowe T, Koliani-Pace J, Smith K, Gordon S, Gardner T
Clin Gastroenterol Hepatol
. 2019 Jan;
17(12):2608-2609.e1.
PMID: 30664949
Pain is the most common and most debilitating aspect of chronic pancreatitis and is difficult to treat. Clinical management of painful chronic pancreatitis includes abstinence from alcohol and tobacco products,...
12.
Park S, Cho H, Thornton A, Barlowe T, Chou T, Chhangawala S, et al.
Cell Stem Cell
. 2018 Nov;
24(1):153-165.e7.
PMID: 30472158
Leukemias exhibit a dysregulated developmental program mediated through both genetic and epigenetic mechanisms. Although IKZF2 is expressed in hematopoietic stem cells (HSCs), we found that it is dispensable for mouse...
13.
Vu L, Prieto C, Amin E, Chhangawala S, Krivtsov A, Calvo-Vidal M, et al.
Nat Genet
. 2017 Apr;
49(6):866-875.
PMID: 28436985
The identity of the RNA-binding proteins (RBPs) that govern cancer stem cells remains poorly characterized. The MSI2 RBP is a central regulator of translation of cancer stem cell programs. Through...
14.
Taggart J, Ho T, Amin E, Xu H, Barlowe T, Perez A, et al.
Nat Commun
. 2016 Feb;
7:10739.
PMID: 26898884
Myelodysplastic syndromes (MDS) are driven by complex genetic and epigenetic alterations. The MSI2 RNA-binding protein has been demonstrated to have a role in acute myeloid leukaemia and stem cell function,...
15.
Li N, Yousefi M, Nakauka-Ddamba A, Li F, Vandivier L, Parada K, et al.
Cell Rep
. 2015 Dec;
13(11):2440-2455.
PMID: 26673327
Members of the Msi family of RNA-binding proteins have recently emerged as potent oncoproteins in a range of malignancies. MSI2 is highly expressed in hematopoietic cancers, where it is required...
16.
Park S, Gonen M, Vu L, Minuesa G, Tivnan P, Barlowe T, et al.
J Clin Invest
. 2015 Feb;
125(3):1286-98.
PMID: 25664853
Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeutic resistance. Leukemia cells exhibit a dysregulated developmental program as the result of genetic and epigenetic...
17.
Land R, Rayne A, Vanderbeck A, Barlowe T, Manjunath S, Gross M, et al.
Stem Cells
. 2014 Oct;
33(1):278-88.
PMID: 25284014
Hematopoiesis is maintained throughout life by self-renewing hematopoietic stem cells (HSCs) that differentiate to produce both myeloid and lymphoid cells. The NR4A family of orphan nuclear receptors, which regulates cell...