Trevor R Carmichael
Overview
Explore the profile of Trevor R Carmichael including associated specialties, affiliations and a list of published articles.
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16
Citations
355
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Recent Articles
1.
Li Z, Wang Z, Lee M, Zenkel M, Peh E, Ozaki M, et al.
JAMA
. 2021 Feb;
325(8):753-764.
PMID: 33620406
Importance: Exfoliation syndrome is a systemic disorder characterized by progressive accumulation of abnormal fibrillar protein aggregates manifesting clinically in the anterior chamber of the eye. This disorder is the most...
2.
Hauser M, Allingham R, Aung T, van der Heide C, Taylor K, Rotter J, et al.
JAMA
. 2019 Nov;
322(17):1682-1691.
PMID: 31688885
Importance: Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations of African ancestry compared with European or Asian ancestry. Despite this, individuals of...
3.
Berner D, Hoja U, Zenkel M, Ross J, Uebe S, Paoli D, et al.
Hum Mol Genet
. 2019 Apr;
28(15):2531-2548.
PMID: 30986821
LOXL1 (lysyl oxidase-like 1) has been identified as the major effect locus in pseudoexfoliation (PEX) syndrome, a fibrotic disorder of the extracellular matrix and frequent cause of chronic open-angle glaucoma....
4.
Goolam S, Carstens N, Ross M, Bentley D, Lopes M, Peden J, et al.
Mol Vis
. 2018 Jun;
24:407-413.
PMID: 29930474
Purpose: To report on a clinical and genetic investigation of a large, multigenerational South African family of mixed ancestry with autosomal dominant congenital cataracts, coloboma, and nystagmus. Methods: Ophthalmic examination...
5.
Aung T, Ozaki M, Lee M, Schlotzer-Schrehardt U, Thorleifsson G, Mizoguchi T, et al.
Nat Genet
. 2017 May;
49(7):993-1004.
PMID: 28553957
Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been...
6.
Hauser M, Aboobakar I, Liu Y, Miura S, Whigham B, Challa P, et al.
Hum Mol Genet
. 2015 Aug;
24(22):6552-63.
PMID: 26307087
Exfoliation syndrome (XFS) is a common, age-related, systemic fibrillinopathy. It greatly increases risk of exfoliation glaucoma (XFG), a major worldwide cause of irreversible blindness. Coding variants in the lysyl oxidase-like...
7.
Williams S, Carmichael T, Allingham R, Hauser M, Ramsay M
Sci Rep
. 2015 Feb;
5:8378.
PMID: 25669751
Multiple loci have been associated with either primary open angle glaucoma (POAG) or heritable ocular quantitative traits associated with this condition. This study examined the association of these loci with...
8.
Moosa R, Choonara Y, du Toit L, Kumar P, Tomar L, Tyagi C, et al.
Pharm Dev Technol
. 2014 Jun;
20(7):854-862.
PMID: 24946794
Ocular diseases of the anterior segment of the eye are increasing and the development of novel drug delivery systems for improved treatment is necessary. The aim of this study was...
9.
Moosa R, Choonara Y, du Toit L, Tomar L, Tyagi C, Kumar P, et al.
Int J Pharm
. 2014 Mar;
466(1-2):296-306.
PMID: 24607446
The purpose of this study was to investigate the in-depth pharmaceutical properties and in vivo behavior of a novel lyophilized rapidly dissolving solid ocular matrix (RD-SOM) as a 'solid eye...
10.
Liu Y, Whigham B, Wheeler J, Williams S, Rautenbach R, Ziskind A, et al.
Mol Vis
. 2013 Jan;
18:2976-81.
PMID: 23288989
Purpose: To investigate whether DNA copy number variants (CNVs) in the lysyl oxidase-like 1 (LOXL1) gene are associated with exfoliation glaucoma (XFG) in black South Africans. Methods: Black South African...