Trevor A Feagin
Overview
Explore the profile of Trevor A Feagin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
126
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Seo D, Heatwole E, Feagin T, Lopez-Pulliam I, Luscher D, Koskelo A, et al.
Sci Rep
. 2024 Jul;
14(1):16695.
PMID: 39030245
This study conducted integrated experiments and computational modeling to investigate the speeds of a developing shock within granular salt and analyzed the effect of various impact velocities up to 245...
2.
Sanford A, Rangel A, Feagin T, Lowery R, Argueta-Gonzalez H, Heemstra J
Chem Sci
. 2021 Oct;
12(35):11692-11702.
PMID: 34659704
Aptamers are widely employed as recognition elements in small molecule biosensors due to their ability to recognize small molecule targets with high affinity and selectivity. Structure-switching aptamers are particularly promising...
3.
Gordon C, Wu D, Pusuluri A, Feagin T, Csordas A, Eisenstein M, et al.
ACS Chem Biol
. 2019 Sep;
14(12):2652-2662.
PMID: 31532184
Base-modified aptamers that incorporate non-natural chemical moieties can achieve greatly improved affinity and specificity relative to natural DNA or RNA aptamers. However, conventional methods for generating base-modified aptamers require considerable...
4.
Feagin T, Maganzini N, Soh H
ACS Sens
. 2018 Aug;
3(9):1611-1615.
PMID: 30156834
Aptamer biosensor that can switch its structure upon target binding offers a powerful strategy for molecular detection. However, the process of converting an aptamer into a "structure-switching" biosensor is challenging...
5.
Gotrik M, Feagin T, Csordas A, Nakamoto M, Soh H
Acc Chem Res
. 2016 Aug;
49(9):1903-10.
PMID: 27526193
Affinity reagents that specifically bind to their target molecules are invaluable tools in nearly every field of modern biomedicine. Nucleic acid-based aptamers offer many advantages in this domain, because they...
6.
Tan Z, Feagin T, Heemstra J
J Am Chem Soc
. 2016 May;
138(20):6328-31.
PMID: 27159220
Aptamer-based sensors provide a versatile and effective platform for the detection of chemical and biological targets. These sensors have been optimized to function in multiple formats, however, a remaining limitation...
7.
Feagin T, Olsen D, Headman Z, Heemstra J
J Am Chem Soc
. 2015 Mar;
137(12):4198-206.
PMID: 25747268
Distinguishing between the two enantiomers of a molecule is a challenging task due to their nearly identical physical properties. Time-consuming chromatography methods are typically required for this task, which greatly...
8.
Feagin T, Shah N, Heemstra J
J Nucleic Acids
. 2012 Aug;
2012:354549.
PMID: 22848796
The peptide nucleic acid backbone Fmoc-AEG-OBn has been synthesized via a scalable and cost-effective route. Ethylenediamine is mono-Boc protected, then alkylated with benzyl bromoacetate. The Boc group is removed and...