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Tracey Allen K Freitas

Explore the profile of Tracey Allen K Freitas including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 282
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Recent Articles
1.
Freitas T, Li P, Scholz M, Chain P
Nucleic Acids Res . 2015 Mar; 43(10):e69. PMID: 25765641
A major challenge in the field of shotgun metagenomics is the accurate identification of organisms present within a microbial community, based on classification of short sequence reads. Though existing microbial...
2.
Rahman A, Usharraj A, Misra B, Thottathil G, Jayasekaran K, Feng Y, et al.
BMC Genomics . 2013 Feb; 14:75. PMID: 23375136
Background: Hevea brasiliensis, a member of the Euphorbiaceae family, is the major commercial source of natural rubber (NR). NR is a latex polymer with high elasticity, flexibility, and resilience that...
3.
Wan X, Tuckerman J, Saito J, Freitas T, Newhouse J, Denery J, et al.
J Mol Biol . 2009 Mar; 388(2):262-70. PMID: 19285985
Globin-coupled sensors are heme-binding signal transducers in Bacteria and Archaea in which an N-terminal globin controls the activity of a variable C-terminal domain. Here, we report that BpeGReg, a globin-coupled...
4.
Saito J, Freitas T, Alam M
Methods Enzymol . 2008 Apr; 437:163-72. PMID: 18433628
Globin-coupled sensors (GCSs) are multidomain proteins, consisting of an N-terminal globin domain fused to a variety of C-terminal transmitter domains. Functional classification of GCSs is based on the transmitter domain(s)...
5.
Freitas T, Saito J, Hou S, Alam M
J Inorg Biochem . 2004 Dec; 99(1):23-33. PMID: 15598488
The strategy for detecting oxygen, carbon monoxide, nitric oxide, and sulfides is predominantly through heme-based sensors utilizing either a globin domain or a PAS domain. Whereas PAS domains bind various...
6.
Freitas T, Hou S, Dioum E, Saito J, Newhouse J, Gonzalez G, et al.
Proc Natl Acad Sci U S A . 2004 Apr; 101(17):6675-80. PMID: 15096613
Hemoglobins are ubiquitous in Eukarya and Bacteria but, until now, have not been found in Archaea. A phylogenetic analysis of the recently revealed microbial family of globin-coupled heme-based sensors suggests...
7.
Freitas T, Hou S, Alam M
FEBS Lett . 2003 Oct; 552(2-3):99-104. PMID: 14527668
The recently discovered globin-coupled sensors (GCSs) are heme-containing two-domain transducers distinct from the PAS domain superfamily. We have identified an additional 22 GCSs with varying multi-domain C-terminal transmitters through a...