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Toshiyuki Kanamori

Explore the profile of Toshiyuki Kanamori including associated specialties, affiliations and a list of published articles. Areas
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Articles 84
Citations 570
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Recent Articles
1.
Tsuyukubo A, Morishita K, Kanamori T, Sumaru K
Biomater Sci . 2023 Jun; 11(15):5129-5135. PMID: 37345713
Herein, we constructed a spheroid array culture system on a flexible hydrogel membrane suspended in the culture medium. When we applied this culture system to HepG2 cells, the results suggested...
2.
Limjanthong N, Tohbaru Y, Okamoto T, Okajima R, Kusama Y, Kojima H, et al.
J Biosci Bioeng . 2022 Dec; 135(2):151-159. PMID: 36586792
Gravity-driven microfluidics, which utilizes gravity force to drive liquid flow, offers portability and multi-condition setting flexibility because they do not require pumps or connection tubes to drive the flow. However,...
3.
Sugiura S, Shin K, Kanamori T
J Biosci Bioeng . 2022 Oct; 135(1):79-85. PMID: 36253250
This paper reports perfusion culture of human umbilical vein endothelial cells (HUVECs) on a microporous membrane in a pressure-driven microphysiological system (PD-MPS), which we developed previously as a multi-throughput perfusion...
4.
Sugiura S, Satoh T, Shin K, Onuki-Nagasaki R, Kanamori T
J Biosci Bioeng . 2022 Aug; 134(4):348-355. PMID: 35963667
Here we report the perfusion culture of a multi-layered tissue composed of HepG2 cells (a human hepatoma line) in a pressure-driven microphysiological system (PD-MPS), which we developed previously as a...
5.
Tsuyukubo A, Sumaru K, Kanamori T
ACS Appl Bio Mater . 2022 Jan; 2(10):4129-4133. PMID: 35021427
Insufficient reliability of current drug screening by cell-based assay has been one of the factors in the poor success rate in drug development. To improve the situation, we proposed a...
6.
Shinohara M, Arakawa H, Oda Y, Shiraki N, Sugiura S, Nishiuchi T, et al.
Sci Rep . 2021 Mar; 11(1):5437. PMID: 33686099
Examining intestine-liver interactions is important for achieving the desired physiological drug absorption and metabolism response in in vitro drug tests. Multi-organ microphysiological systems (MPSs) constitute promising tools for evaluating inter-organ...
7.
Baba T, Takagi T, Sumaru K, Kanamori T, Dewa T, Nango M
Colloids Surf B Biointerfaces . 2020 Nov; 198:111459. PMID: 33248875
To examine the applicability of fluorinated membrane-forming phospholipids to reconstitution matrices for functional membrane proteins, the membrane properties of a synthetic ether-type phosphatidylcholine (PC) bearing partially fluorinated C-monoacetylenic (9-octadecynyl) chains,...
8.
Figarol A, Piantino M, Furihata T, Satoh T, Sugiura S, Kanamori T, et al.
Biochem Biophys Res Commun . 2020 Sep; 533(3):600-606. PMID: 32988592
Cell culture under medium flow has been shown to favor human brain microvascular endothelial cells function and maturation. Here a three-dimensional in vitro model of the human brain microvasculature, comprising...
9.
Yamahira S, Satoh T, Yanagawa F, Tamura M, Takagi T, Nakatani E, et al.
R Soc Open Sci . 2020 Sep; 7(7):200027. PMID: 32874617
Inside living organisms, concentration gradients dynamically change over time as biological processes progress. Therefore, methods to construct dynamic microscale concentration gradients in a spatially controlled manner are needed to provide...
10.
Watanabe U, Sugiura S, Kakehata M, Yanagawa F, Takagi T, Sumaru K, et al.
Micromachines (Basel) . 2020 Jul; 11(7). PMID: 32668567
Engineered blood vessels generally recapitulate vascular function in vitro and can be utilized in drug discovery as a novel microphysiological system. Recently, various methods to fabricate vascular models in hydrogels...