Toshihide Ueno
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Explore the profile of Toshihide Ueno including associated specialties, affiliations and a list of published articles.
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Articles
94
Citations
3825
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Recent Articles
1.
Hirose T, Ikegami M, Kida K, Ueno T, Kitada R, Wang L, et al.
NPJ Breast Cancer
. 2024 Oct;
10(1):87.
PMID: 39366967
Patients with germline pathogenic variants of BRCA1/2 genes have a particular predisposition to develop breast cancer. No clinical test has been developed to accurately and quantitatively evaluate their risk of...
2.
Ikeuchi H, Matsuno Y, Kusumoto-Matsuo R, Kojima S, Ueno T, Ikegami M, et al.
Oncogene
. 2024 Sep;
43(41):3079.
PMID: 39271966
No abstract available.
3.
Mukohara F, Iwata K, Ishino T, Inozume T, Nagasaki J, Ueda Y, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(35):e2320189121.
PMID: 39167601
Immune checkpoint inhibitors (ICIs) exert clinical efficacy against various types of cancers by reinvigorating exhausted CD8 T cells that can expand and directly attack cancer cells (cancer-specific T cells) among...
4.
Ikeuchi H, Matsuno Y, Kusumoto-Matsuo R, Kojima S, Ueno T, Ikegami M, et al.
Oncogene
. 2024 Aug;
43(41):3037-3048.
PMID: 39095584
Identifying the mechanisms of action of anticancer drugs is an important step in the development of new drugs. In this study, we established a comprehensive screening platform consisting of 68...
5.
Kawase K, Taguchi A, Ishizaka A, Lin J, Ueno T, Yoshimoto D, et al.
HLA
. 2024 Jun;
103(6):e15509.
PMID: 38837741
Loss of heterozygosity (LOH) has been reported to occur in HLA regions in cervical intraepithelial neoplasia (CIN) and cervical cancer. However, the details of how this is related to the...
6.
Machitani M, Nomura A, Yamashita T, Yasukawa M, Ueki S, Fujita K, et al.
Nat Cell Biol
. 2024 May;
26(6):932-945.
PMID: 38806647
As aberrant accumulation of RNA-DNA hybrids (R-loops) causes DNA damage and genome instability, cells express regulators of R-loop structures. Here we report that RNA-dependent RNA polymerase (RdRP) activity of human...
7.
Kohsaka S, Yagishita S, Shirai Y, Matsuno Y, Ueno T, Kojima S, et al.
NPJ Precis Oncol
. 2024 May;
8(1):117.
PMID: 38789724
E7820 and Indisulam (E7070) are sulfonamide molecular glues that modulate RNA splicing by degrading the splicing factor RBM39 via ternary complex formation with the E3 ligase adaptor DCAF15. To identify...
8.
Torasawa M, Yoshida T, Shiraishi K, Goto N, Ueno T, Ichikawa H, et al.
JTO Clin Res Rep
. 2024 May;
5(4):100657.
PMID: 38706977
Lenvatinib, a multitarget tyrosine kinase inhibitor for c-Kit and other kinases, has exhibited promising efficacy in treating advanced or metastatic thymic carcinoma (TC). Here, we present the case of a...
9.
Torasawa M, Shukuya T, Uemura K, Hayashi T, Ueno T, Kohsaka S, et al.
Respirology
. 2024 Apr;
29(9):815-824.
PMID: 38654512
Background And Objective: Lymphangioleiomyomatosis (LAM) is a rare neoplastic disease associated with the functional tumour suppressor genes TSC1 and TSC2 and causes structural destruction in the lungs, which could potentially...
10.
Shirai Y, Ueno T, Kojima S, Ikeuchi H, Kitada R, Koyama T, et al.
J Neurooncol
. 2024 Feb;
167(1):75-88.
PMID: 38363490
Purpose: Various molecular profiles are needed to classify malignant brain tumors, including gliomas, based on the latest classification criteria of the World Health Organization, and their poor prognosis necessitates new...