Toru Okamoto
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Explore the profile of Toru Okamoto including associated specialties, affiliations and a list of published articles.
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124
Citations
3739
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Recent Articles
1.
Suzuki Y, Miyazaki T, Ida Y, Suzuki T, Itoh Y, Nakao S, et al.
Mol Ther Nucleic Acids
. 2025 Mar;
36(1):102467.
PMID: 40027884
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants repeatedly evade the immune system within short periods. Thus, next-generation therapeutics that are resistant to mutations and can be rapidly supplied to individuals...
2.
Suzuki H, Suzuki M, Jimbo K, Hibio M, Sasaki T, Murai T, et al.
Clin Chim Acta
. 2024 Nov;
566:120060.
PMID: 39581249
Objective: Effect of gut dysbiosis on fatty acid (FA) linked 3β-hydroxy-bile acid esters (FA-isoBAs) formation is currently unknown. This study aimed to investigate the profile of FA-isoBAs in fecal samples...
3.
Shigeno S, Kodama T, Murai K, Motooka D, Fukushima A, Nishio A, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Sep;
19(1):101412.
PMID: 39349249
Background & Aims: Targeting exhausted immune systems would be a promising therapeutic strategy to achieve a functional cure for HBV infection in patients with chronic hepatitis B (CHB). However, animal...
4.
Okamoto T, Itoh Y, Suzuki T
Uirusu
. 2024 Sep;
73(2):163-172.
PMID: 39343551
It has been passed four years since the pandemic caused by the severe acute respiratory syndrome-2 (SARS-CoV-2) that began in 2019. Since June 2020, we have been working on a...
5.
Itoh Y, Miyamoto Y, Tokunaga M, Suzuki T, Takada A, Ninomiya A, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012409.
PMID: 39146232
Flaviviridae is a family of positive-stranded RNA viruses, including human pathogens, such as Japanese encephalitis virus (JEV), dengue virus (DENV), Zika virus (ZIKV), and West Nile virus (WNV). Nuclear localization...
6.
Hirano J, Hayashi T, Kitamura K, Nishimura Y, Shimizu H, Okamoto T, et al.
J Virol
. 2024 Jun;
98(7):e0081324.
PMID: 38904364
Enteroviruses are single-stranded, positive-sense RNA viruses causing endoplasmic reticulum (ER) stress to induce or modulate downstream signaling pathways known as the unfolded protein responses (UPR). However, viral and host factors...
7.
Sakata T, Yoshio S, Yamazoe T, Mori T, Kakazu E, Aoki Y, et al.
Front Immunol
. 2024 Apr;
15:1389411.
PMID: 38638429
Introduction: Natural killer (NK) cells play a pivotal role in immune surveillance in the liver. We aimed to identify potential targets for NK cell-mediated immune intervention by revealing the functional...
8.
Minami S, Kotaki T, Sakai Y, Okamura S, Torii S, Ono C, et al.
Microbiol Spectr
. 2024 Feb;
12(4):e0285923.
PMID: 38415690
Importance: The efficacy of the S protein cleavage generally differs among the SARS-CoV-2 variants, resulting in distinct viral characteristics. The relationship between a mutation and the entry of SARS-CoV-2 into...
9.
Fujimoto K, Kameda Y, Nagano Y, Deguchi S, Yamamoto T, Krol R, et al.
Lab Chip
. 2024 Jan;
24(16):3863-3879.
PMID: 38252025
Blood vessels show various COVID-19-related conditions including thrombosis and cytokine propagation. Existing blood vessel models cannot represent the consequent changes in the vascular structure or determine the initial infection site,...
10.
Samune Y, Saito A, Sasaki T, Koketsu R, Srimark N, Phadungsombat J, et al.
PLoS Negl Trop Dis
. 2024 Jan;
18(1):e0011885.
PMID: 38190404
Dengue is a mosquito-borne disease that has spread to over 100 countries. Its symptoms vary from the relatively mild acute febrile illness called dengue fever to the much more severe...