Toomas Haller
Overview
Explore the profile of Toomas Haller including associated specialties, affiliations and a list of published articles.
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47
Citations
8665
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Recent Articles
1.
Nurm M, Reigo A, Annilo T, Toomsoo T, Noukas M, Nikopensius T, et al.
Eur J Hum Genet
. 2024 Dec;
PMID: 39674827
Population-based biobanks enable genomic screening to support initiatives that prevent disease onset or slow its progression and to estimate the prevalence of genetic diseases in the population. Wilson's disease (WD)...
2.
Figueredo J, Krebs K, Pujol-Gualdo N, Haller T, Vosa U, Volke V, et al.
Eur J Endocrinol
. 2024 Jul;
191(2):211-222.
PMID: 39067062
Objective: The aim of the study is to map the shared genetic component and relationships between thyroid and reproductive health traits to improve the understanding of the interplay between those...
3.
Karjalainen M, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung W, et al.
Nature
. 2024 Mar;
628(8006):130-138.
PMID: 38448586
Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism. This detailed knowledge of the genetic determinants of systemic metabolism has been...
4.
Frkatovic-Hodzic A, Mijakovac A, Miskec K, Nostaeva A, Sharapov S, Landini A, et al.
Aging (Albany NY)
. 2023 Dec;
15(24):14509-14552.
PMID: 38149987
Glycans are an essential structural component of immunoglobulin G (IgG) that modulate its structure and function. However, regulatory mechanisms behind this complex posttranslational modification are not well known. Previous genome-wide...
5.
Oja K, Ilisson M, Reinson K, Muru K, Reimand T, Peterson H, et al.
medRxiv
. 2023 Apr;
PMID: 37034709
Introduction: Epilepsy is a common central nervous system disorder characterized by abnormal brain electrical activity. We aimed to compare the metabolic profiles of plasma from patients with epilepsy across different...
6.
Kurvits S, Harro A, Reigo A, Ott A, Laur S, Sarg D, et al.
Eur J Med Res
. 2023 Mar;
28(1):133.
PMID: 36966315
Background: Ischemic stroke (IS) is a major health risk without generally usable effective measures of primary prevention. Early warning signals that are easy to detect and widely available can save...
7.
Sadegh S, Skelton J, Anastasi E, Maier A, Adamowicz K, Moller A, et al.
Nat Commun
. 2023 Mar;
14(1):1662.
PMID: 36966134
A long-term objective of network medicine is to replace our current, mainly phenotype-based disease definitions by subtypes of health conditions corresponding to distinct pathomechanisms. For this, molecular and health data...
8.
Musolf A, Haarman A, Luben R, Ong J, Patasova K, Trapero R, et al.
Commun Biol
. 2023 Jan;
6(1):6.
PMID: 36596879
Refractive error, measured here as mean spherical equivalent (SER), is a complex eye condition caused by both genetic and environmental factors. Individuals with strong positive or negative values of SER...
9.
Saunders G, Wang X, Chen F, Jang S, Liu M, Wang C, et al.
Nature
. 2022 Dec;
612(7941):720-724.
PMID: 36477530
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide deaths, respectively, due largely to broad increased risk for disease and injury. These substances are used...
10.
Wang Z, Emmerich A, Pillon N, Moore T, Hemerich D, Cornelis M, et al.
Nat Genet
. 2022 Sep;
54(9):1332-1344.
PMID: 36071172
Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in...