Tony R Bai
Overview
Explore the profile of Tony R Bai including associated specialties, affiliations and a list of published articles.
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22
Citations
802
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Recent Articles
1.
James A, Noble P, Drew S, Mauad T, Bai T, Abramson M, et al.
J Appl Physiol (1985)
. 2018 Jul;
125(4):1090-1096.
PMID: 30024335
In asthma, it is unclear if the airway smooth muscle cells proliferate more or are increased at the onset of asthma and remain stable. This study aimed to compare smooth...
2.
Elliot J, Noble P, Mauad T, Bai T, Abramson M, McKay K, et al.
Respirology
. 2018 Jun;
23(12):1138-1145.
PMID: 29943875
Background And Objective: The pathology of asthma is characterized by airway inflammation (granulocytic (GA) or paucigranulocytic (PGA)) and remodelling of airway structures. However, the relationship between inflammatory phenotypes and remodelling...
3.
Elliot J, Jones R, Abramson M, Green F, Mauad T, McKay K, et al.
Respirology
. 2014 Sep;
20(1):66-72.
PMID: 25257809
Background And Objective: Pathological phenotypes of asthma have been based predominantly on inflammation, rather than airway wall remodelling. Differences in the distribution of airway smooth muscle (ASM) remodelling between large...
4.
Cruz-Sanchez T, Haddrell A, Hackett T, Singhera G, Marchant D, Lekivetz R, et al.
Anal Chem
. 2012 Dec;
85(2):898-906.
PMID: 23205519
Epidemiological associations of worse respiratory outcomes from combined exposure to ambient particulate matter (PM) and respiratory viral infection suggest possible interactions between PM and viruses. To characterize outcomes of such...
5.
James A, Elliot J, Jones R, Carroll M, Mauad T, Bai T, et al.
Am J Respir Crit Care Med
. 2012 Mar;
185(10):1058-64.
PMID: 22403800
Rationale: Increased thickness of the airway smooth muscle (ASM) layer in asthma may result from hyperplasia or hypertrophy of muscle cells or increased extracellular matrix (ECM). Objectives: To relate ASM...
6.
Hackett T, Singhera G, Shaheen F, Hayden P, Jackson G, Hegele R, et al.
Am J Respir Cell Mol Biol
. 2011 Jun;
45(5):1090-100.
PMID: 21642587
A substantial proportion of healthcare cost associated with asthma is attributable to exacerbations of the disease. Within the airway, the epithelium forms the mucosal immune barrier, the first structural cell...
7.
Bai T
Curr Opin Allergy Clin Immunol
. 2009 Oct;
10(1):82-6.
PMID: 19858714
Purpose Of Review: This review focuses on recent findings in relation to potential functional consequences of structural changes in the asthmatic airway. Recent Findings: Increases in smooth muscle mass have...
8.
Hackett T, Warner S, Stefanowicz D, Shaheen F, Pechkovsky D, Murray L, et al.
Am J Respir Crit Care Med
. 2009 May;
180(2):122-33.
PMID: 19406982
Rationale: Airway remodeling in asthma is associated with the accumulation of fibroblasts, the primary cell responsible for synthesis and secretion of extracellular matrix proteins. The process by which the number...
9.
McTaggart-Cowan H, Shi P, FitzGerald J, Anis A, Kopec J, Bai T, et al.
J Asthma
. 2008 Oct;
45(8):630-8.
PMID: 18951253
Background: Not taking treatment preferences into account may lead to patients' inappropriate use of asthma treatments. The objective of this study was to quantify these preferences, in terms of risk-benefits...
10.
James A, Green F, Abramson M, Bai T, Dolhnikoff M, Mauad T, et al.
J Appl Physiol (1985)
. 2008 Mar;
104(6):1703-8.
PMID: 18369095
The perimeter of the basement membrane (Pbm) of an airway viewed in cross section is used as a marker of airway size because in normal lungs it is relatively constant,...