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Tongxiang Lin

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Articles 27
Citations 2891
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Recent Articles
1.
Wu S, Rong C, Lin R, Ji K, Lin T, Chen W, et al.
Front Immunol . 2024 Aug; 15:1410784. PMID: 39156892
Background: PaBing-II Formula (PB-II) is a traditional Chinese medicine for treating Parkinson's disease (PD). However, owing to the complexity of PB-II and the difficulty in obtaining human dopaminergic neurons (DAn),...
2.
Wu S, Lin T, Xu Y
Cell Mol Life Sci . 2023 Nov; 80(12):363. PMID: 37981592
Parkinson's disease (PD) is one of the most common neuro-degenerative diseases characterized by α-synuclein accumulation and degeneration of dopaminergic neurons. Employing genome-wide sequencing, we identified a polymorphic USP8 allele (USP8)...
3.
Wei R, Rong C, Xie Q, Wu S, Feng Y, Wang R, et al.
Evid Based Complement Alternat Med . 2020 Jan; 2019:2529641. PMID: 31929812
Parkinson's disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra (SN)-striatum circuit, which is associated with glial activation and consequent chronic neuroinflammation. Optimized Yinxieling Formula...
4.
Wei R, Ouyang J, Lin W, Lin T
Evid Based Complement Alternat Med . 2018 Dec; 2018:6142065. PMID: 30519267
Parkinson's disease (PD) is marked by the progressive degeneration of dopaminergic neurons (DAN) accompanied by glial activation. Thus, inhibiting glial activation that occurs during this disease could be an effective...
5.
Lin T, Lin Y
Stem Cell Res Ther . 2017 Mar; 8(1):44. PMID: 28241890
The role of p53 as "a guardian of the genome" has been well established in somatic cells. However, its role in pluripotent stem cells remains much more elusive. Here, we...
6.
Zhang Q, Chen W, Tan S, Lin T
Hum Gene Ther . 2016 Oct; 28(1):85-98. PMID: 27762639
Parkinson's disease (PD) is the second most frequent neurodegenerative disease after Alzheimer's disease, which is characterized by a low level of dopamine being expressing in the striatum and a deterioration...
7.
Jin X, Lin T, Xu Y
Curr Mol Pharmacol . 2015 Sep; 9(4):284-288. PMID: 26415913
With their capability to undergo unlimited self-renew and to differentiate into various functional cells, human pluripotent stem cells, including embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), hold...
8.
Zhao T, Zhang Z, Westenskow P, Todorova D, Hu Z, Lin T, et al.
Cell Stem Cell . 2015 Aug; 17(3):353-9. PMID: 26299572
The breakthrough of induced pluripotent stem cell (iPSC) technology has raised the possibility that patient-specific iPSCs may become a renewable source of autologous cells for cell therapy without the concern...
9.
Feng M, Lu A, Gao H, Qian C, Zhang J, Lin T, et al.
Stem Cells Int . 2015 Aug; 2015:325652. PMID: 26236347
This retrospective study aimed to assess the safety of patients with severe cerebral palsy (CP), who received allogeneic umbilical cord blood stem cells (UCBSCs) treatment from August 2009 to December...
10.
Lin T, Wu S
Stem Cells Int . 2015 Apr; 2015:794632. PMID: 25922608
Induced pluripotent stem cells (iPSCs) could be employed in the creation of patient-specific stem cells, which could subsequently be used in various basic and clinical applications. However, current iPSC methodologies...