Tommi H Nyronen
Overview
Explore the profile of Tommi H Nyronen including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
243
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0
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Recent Articles
1.
Kukkonen-Macchi A, Hautaniemi S, Heil K, Heinaniemi M, Jensen L, Junttila S, et al.
Bioinformatics
. 2024 Sep;
40(Suppl 2):ii1-ii3.
PMID: 39230712
No abstract available.
2.
Thorogood A, Rehm H, Goodhand P, Page A, Joly Y, Baudis M, et al.
Cell Genom
. 2022 Feb;
1(2).
PMID: 35128509
We promote a shared vision and guide for how and when to federate genomic and health-related data sharing, enabling connections and insights across independent, secure databases. The GA4GH encourages a...
3.
Rehm H, Page A, Smith L, Adams J, Alterovitz G, Babb L, et al.
Cell Genom
. 2022 Jan;
1(2).
PMID: 35072136
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated...
4.
Voisin C, Linden M, Dyke S, Bowers S, Alper P, Barkley M, et al.
Cell Genom
. 2021 Nov;
1(2):None.
PMID: 34820660
The Global Alliance for Genomics and Health (GA4GH) supports international standards that enable a federated data sharing model for the research community while respecting data security, ethical and regulatory frameworks,...
5.
Lawson J, Cabili M, Kerry G, Boughtwood T, Thorogood A, Alper P, et al.
Cell Genom
. 2021 Nov;
1(2):None.
PMID: 34820659
Human biomedical datasets that are critical for research and clinical studies to benefit human health also often contain sensitive or potentially identifying information of individual participants. Thus, care must be...
6.
Papaioannou M, Soderholm A, Hong W, Dai Y, Roediger J, Roell D, et al.
Anticancer Agents Med Chem
. 2012 Dec;
13(5):801-10.
PMID: 23194423
Androgen receptor (AR) antagonists are important compounds for the treatment of prostate cancer (PCa). The atraric acid (AA), a natural compound, binds to the AR and acts as a specific...
7.
Nyronen T, Soderholm A
Expert Opin Drug Discov
. 2012 Jul;
5(1):5-20.
PMID: 22823968
Importance Of The Field: Deep structural and chemical understanding of the protein target and computational methods for detection of receptor-selective ligands are important for the early drug discovery in the...
8.
Schneider M, Walter P, Blatter M, Watson J, Brazas M, Rother K, et al.
Brief Bioinform
. 2011 Nov;
13(3):383-9.
PMID: 22110242
Funding bodies are increasingly recognizing the need to provide graduates and researchers with access to short intensive courses in a variety of disciplines, in order both to improve the general...
9.
Soderholm A, Viiliainen J, Lehtovuori P, Eskelinen H, Roell D, Baniahmad A, et al.
J Chem Inf Model
. 2008 Aug;
48(9):1882-90.
PMID: 18712859
We have identified and profiled a set of androgen receptor (AR) binding compounds representing two nonsteroidal scaffolds from a public chemical database supplied by Asinex with virtual screening procedure incorporating...
10.
Soderholm A, Lehtovuori P, Nyronen T
J Med Chem
. 2006 Jul;
49(14):4261-8.
PMID: 16821785
We report a docking and comparative molecular similarity indices analysis (CoMSIA) study of progesterone receptor (PR) ligands with an emphasis on nonsteroids including tanaproget. The ligand alignment generation, a critical...