Tommaso Bonfiglio
Overview
Explore the profile of Tommaso Bonfiglio including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
237
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Recent Articles
1.
Muzyka M, Ottaviani S, Caffa I, Bonfiglio T, Parisi E, Guijarro A, et al.
Cancers (Basel)
. 2025 Mar;
17(5).
PMID: 40075636
Multiple myeloma (MM) is a plasma cell neoplasm predominantly diagnosed in older adults. However, the significance of defining patient frailty, as well as identifying the most suitable and reliable tools...
2.
Tagliafico L, Da Costa R, Boccia L, Kavehmoghaddam S, Ramirez B, Tokarska-Schlattner M, et al.
Aging Cell
. 2024 Aug;
23(11):e14289.
PMID: 39102875
Neuronal senescence is a major risk factor for the development of many neurodegenerative disorders. The mechanisms that drive neurons to senescence remain largely elusive; however, dysregulated mitochondrial physiology seems to...
3.
Bonfiglio T, Olivero G, Merega E, Di Prisco S, Padolecchia C, Grilli M, et al.
PLoS One
. 2023 Oct;
18(10):e0292584.
PMID: 37788283
[This corrects the article DOI: 10.1371/journal.pone.0170825.].
4.
Rangan P, Lobo F, Parrella E, Rochette N, Morselli M, Stephen T, et al.
Cell Rep
. 2022 Sep;
40(13):111417.
PMID: 36170815
The effects of fasting-mimicking diet (FMD) cycles in reducing many aging and disease risk factors indicate it could affect Alzheimer's disease (AD). Here, we show that FMD cycles reduce cognitive...
5.
Valdemarin F, Caffa I, Persia A, Cremonini A, Ferrando L, Tagliafico L, et al.
Cancers (Basel)
. 2021 Aug;
13(16).
PMID: 34439167
In preclinical studies, fasting was found to potentiate the effects of several anticancer treatments, and early clinical studies indicated that patients may benefit from regimes of modified fasting. However, concerns...
6.
SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice
Becherini P, Caffa I, Piacente F, Damonte P, Vellone V, Passalacqua M, et al.
Cancer Metab
. 2021 Jan;
9(1):6.
PMID: 33482921
Background: Sirtuin 6 (SIRT6) is a NAD-dependent deacetylase with key roles in cell metabolism. High SIRT6 expression is associated with adverse prognosis in breast cancer (BC) patients. However, the mechanisms...
7.
Boggia R, Turrini F, Roggeri A, Olivero G, Cisani F, Bonfiglio T, et al.
Int J Mol Sci
. 2020 May;
21(10).
PMID: 32455600
The immune system and the central nervous system message each other to preserving central homeostasis. Both systems undergo changes during aging that determine central age-related defects. Ellagic acid (EA) is...
8.
Bonfiglio T, Biggi F, Bassi A, Ferrando S, Gallus L, Loiacono F, et al.
Heliyon
. 2019 Jul;
5(6):e01798.
PMID: 31338440
Alterations in the control of apoptotic processes were observed in cells during space flight or under simulated microgravity, the latter obtained with the 3D-Random Positioning Machine (3D-RPM). Usually the proteins...
9.
Olivero G, Grilli M, Vergassola M, Bonfiglio T, Padolecchia C, Garrone B, et al.
Neuropharmacology
. 2018 Mar;
133:429-439.
PMID: 29499271
Presynaptic mGlu2/3 autoreceptors exist in rat spinal cord nerve terminals as suggested by the finding that LY379268 inhibited the 15 mM KCl-evoked release of [H]D-aspartate ([H]D-Asp) in a LY341495-sensitive manner....
10.
Bonfiglio T, Vergassola M, Olivero G, Pittaluga A
Curr Med Chem
. 2018 Mar;
26(20):3670-3684.
PMID: 29493441
Background: Aging is an unavoidable, physiological process that reduces the complexity and the plasticity of the synaptic contacts in Central Nervous System (CNS), having profound implications for human well-being. The...