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Tomi Nousiainen

Explore the profile of Tomi Nousiainen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 56
Followers 0
Related Specialties
General Medicine
Biochemistry
Molecular Biology
Top 10 Co-Authors
Petri Lehenkari
Maarit Valkealahti
Sanna Turunen
Sanna Palosaari
Susanna Yli-Luukko
Olli Vuolteenaho
Anna Karjalainen
Johanna Veijola
Johanna A Huhtakangas
Johanna Huhtakangas
Published In
Arthritis Res Ther
PLoS One
J Steroid Biochem Mol Biol
BMC Musculoskelet Disord
Data Brief
Affiliations
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Recent Articles
1.
Differential synovial tissue expression of TLRs in seropositive and seronegative rheumatoid arthritis: A preliminary report
Abdelwahab A, Palosaari S, Abdelwahab S, Rifaai R, El-Tahawy N, Saber E, et al.
Autoimmunity . 2020 Dec; 54(1):23-34. PMID: 33377396
Toll-like receptors (TLRs) are known to have an important role in triggering the innate immune response and in priming antigen-specific adaptive immunity and inflammation. The differences in synovial tissue expression...
2.
Retention of metals in periprosthetic tissues of patients with metal-on-metal total hip arthroplasty is reflected in the synovial fluid to blood cobalt transfer ratio in the presence of a pseudotumour
Nousiainen T, Palosaari S, Peraniemi S, Tervahauta A, Niinimaki J, Leppilahti J, et al.
BMC Musculoskelet Disord . 2020 Sep; 21(1):610. PMID: 32919463
Background: Modern metal-on-metal (MOM) arthroplasties were performed for over a decade before alarming reports of adverse metal reactions dramatically reduced their use. Failures are seen more often with high-wearing implants,...
3.
Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio
Luukkonen J, Pascual L, Patlaka C, Lang P, Turunen S, Halleen J, et al.
PLoS One . 2017 Aug; 12(8):e0182904. PMID: 28792533
Background: Osteopontin (OPN) is an immunoregulatory protein which production increases in both rheumatoid arthritis (RA) and osteoarthritis (OA). Phosphorylated osteopontin (Phospho-OPN) is known to increase macrophage and osteoclast activation, this...
4.
Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis
Huhtakangas J, Veijola J, Turunen S, Karjalainen A, Valkealahti M, Nousiainen T, et al.
Data Brief . 2017 May; 12:593-602. PMID: 28540351
In this article, we share the raw cytokine data obtained from basal and stimulated synovial stromal cells cultured from patients with rheumatoid arthritis or osteoarthritis. This data article is related...
5.
1,25(OH)D and calcipotriol, its hypocalcemic analog, exert a long-lasting anti-inflammatory and anti-proliferative effect in synoviocytes cultured from patients with rheumatoid arthritis and osteoarthritis
Huhtakangas J, Veijola J, Turunen S, Karjalainen A, Valkealahti M, Nousiainen T, et al.
J Steroid Biochem Mol Biol . 2017 Feb; 173:13-22. PMID: 28167299
Objectives: We investigated the effects of 1,25-dihydroxy vitamin D (1,25(OH)D), i.e. biologically active vitamin D and calcipotriol, a vitamin D analog, on growth and secretion of inflammatory mediators in synovial...
6.
Rheumatoid arthritis antigens homocitrulline and citrulline are generated by local myeloperoxidase and peptidyl arginine deiminases 2, 3 and 4 in rheumatoid nodule and synovial tissue
Turunen S, Huhtakangas J, Nousiainen T, Valkealahti M, Melkko J, Risteli J, et al.
Arthritis Res Ther . 2016 Oct; 18(1):239. PMID: 27765067
Background: Seropositive rheumatoid arthritis (RA) is characterized by autoantibodies binding to citrullinated and homocitrullinated proteins. We wanted to study the expression patterns of these disease-associated protein forms and if the...