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Tomasz Goslinski

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Articles 53
Citations 521
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Recent Articles
1.
Sysak S, Wicher B, Kucinska M, Kobylka P, Mlynarczyk D, Lesyk R, et al.
Sci Rep . 2025 Mar; 15(1):7385. PMID: 40033039
Cancer remains one of the most significant health issues worldwide. By designing compounds with anticancer activity characterized by high selectivity towards cancer cells, medicinal chemistry focuses on the protection of...
2.
Kobylka P, Bakun P, Kuzminska J, Goslinski T, Murias M, Kucinska M
Molecules . 2025 Jan; 30(2). PMID: 39860164
Although curcumin is a well-known natural polyphenol with many biological activities, its clinical application has been limited by low aqueous solubility and stability. Therefore, curcumin derivatives have been proposed to...
3.
Kuzminska J, Szyk P, Mlynarczyk D, Bakun P, Muszalska-Kolos I, Dettlaff K, et al.
Molecules . 2024 Nov; 29(22). PMID: 39598712
Curcumin, a naturally occurring compound found in the rhizome of plants, particularly in turmeric ( L.), exhibits a broad range of biological activities, including anti-inflammatory, antioxidant, and anticancer properties. Curcumin...
4.
Tiwari M, Goslinski T
Bioorg Chem . 2024 Oct; 153:107893. PMID: 39454496
The International Agency for Research on Cancer (IARC) recently estimated the global cancer burden in 2050. The statistics are startling, with a 77% hike and 35 million new cancer cases...
5.
Bakun P, Wysocki M, Stachowiak M, Musielak M, Dlugaszewska J, Mlynarczyk D, et al.
Molecules . 2024 Oct; 29(19). PMID: 39407467
Over the past few years, numerous bacterial strains have become resistant to selected drugs from various therapeutic groups. A potential tool in the fight against these strains is antimicrobial photodynamic...
6.
Czarczynska-Goslinska B, Goslinski T, Roszak A, Froelich A, Szyk P, Mlynarczyk D, et al.
Methods Protoc . 2024 Sep; 7(5). PMID: 39311374
The article aims to outline the potential of treating malignant skin cancer with microneedles covered with polymer layers containing a photosensitizer-protoporphyrin IX disodium salt (PPIX). The usefulness of stereolithography (SLA),...
7.
Szyk P, Czarczynska-Goslinska B, Mlynarczyk D, Slusarska B, Kocki T, Ziegler-Borowska M, et al.
Nanomaterials (Basel) . 2023 Oct; 13(19). PMID: 37836288
Many purine derivatives are active pharmaceutical ingredients of significant importance in the therapy of autoimmune diseases, cancers, and viral infections. In many cases, their medical use is limited due to...
8.
Bakun P, Mlynarczyk D, Koczorowski T, Cerbin-Koczorowska M, Piwowarczyk L, Kolasinski E, et al.
Eur J Med Chem . 2023 Sep; 261:115820. PMID: 37776575
Epigallocatechin gallate (EGCG) is a polyphenol present in green tea (Camellia sinensis), which has revealed anti-cancer effects toward a variety of cancer cells in vitro and protective potential against neurodegenerative...
9.
Sysak S, Czarczynska-Goslinska B, Szyk P, Koczorowski T, Mlynarczyk D, Szczolko W, et al.
Nanomaterials (Basel) . 2023 May; 13(9). PMID: 37177076
Flavonoids are polyphenolic compounds widely occurring throughout the plant kingdom. They are biologically active and have many medical applications. Flavonoids reveal chemopreventive, anticarcinogenic, and antioxidant properties, as well as being...
10.
Lazewski D, Kucinska M, Potapskiy E, Kuzminska J, Popenda L, Tezyk A, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674983
Curcumin has been modified in various ways to broaden its application in medicine and address its limitations. In this study, we present a series of curcumin-based derivatives obtained by replacing...