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Tom Van Maerken

Explore the profile of Tom Van Maerken including associated specialties, affiliations and a list of published articles. Areas
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Articles 49
Citations 965
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Recent Articles
1.
Mutluoglu G, De Muynck B, Emonds M, Van Maerken T
J Pediatr Hematol Oncol . 2025 Jan; 47(2):e125-e127. PMID: 39792822
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) results from maternal antibodies targeting fetal platelets during pregnancy, often causing hemorrhagic manifestations detectable antenatally or shortly after birth. We report an atypical form...
2.
Van Goethem A, Deleu J, Yigit N, Everaert C, Moreno-Smith M, Vasudevan S, et al.
NAR Cancer . 2023 Jan; 5(1):zcad002. PMID: 36683916
Accurate assessment of treatment response and residual disease is indispensable for the evaluation of cancer treatment efficacy. However, performing tissue biopsies for longitudinal follow-up poses a major challenge in the...
3.
Deleu J, Schoofs K, Decock A, Verniers K, Roelandt S, Denolf A, et al.
Hum Genomics . 2022 Dec; 16(1):73. PMID: 36587211
Background: Blood plasma, one of the most studied liquid biopsies, contains various molecules that have biomarker potential for cancer detection, including cell-free DNA (cfDNA) and cell-free RNA (cfRNA). As the...
4.
Vermeirssen V, Deleu J, Morlion A, Everaert C, De Wilde J, Anckaert J, et al.
NAR Cancer . 2022 Dec; 4(4):zcac037. PMID: 36451702
While cell-free DNA (cfDNA) is widely being investigated, free circulating RNA (extracellular RNA, exRNA) has the potential to improve cancer therapy response monitoring and detection due to its dynamic nature....
5.
Gamble L, Purgato S, Henderson M, Di Giacomo S, Russell A, Pigini P, et al.
Cancers (Basel) . 2021 Apr; 13(8). PMID: 33918978
Ornithine decarboxylase (ODC1), a critical regulatory enzyme in polyamine biosynthesis, is a direct transcriptional target of MYCN, amplification of which is a powerful marker of aggressive neuroblastoma. A single nucleotide...
6.
Van Maerken T, De Brabandere E, Noel A, Coorevits L, De Waegemaeker P, Ablorh R, et al.
Antimicrob Resist Infect Control . 2019 Sep; 8:152. PMID: 31548884
Background: We report a recurrent outbreak of postoperative infections with extended-spectrum β-lactamase (ESBL)-producing complex in cardiac surgery patients, describe the outbreak investigation and highlight the infection control measures. Methods: Cases...
7.
Lefever S, Rihani A, Van der Meulen J, Pattyn F, Van Maerken T, Van Dorpe J, et al.
Sci Rep . 2019 Feb; 9(1):2150. PMID: 30770838
For a wide range of diseases, SNPs in the genome are the underlying mechanism of dysfunction. Therefore, targeted detection of these variations is of high importance for early diagnosis and...
8.
Claeys S, Denecker G, Durinck K, Decaesteker B, Mus L, Loontiens S, et al.
Oncogene . 2018 Dec; 38(15):2690-2705. PMID: 30538293
ALK mutations occur in 10% of primary neuroblastomas and represent a major target for precision treatment. In combination with MYCN amplification, ALK mutations infer an ultra-high-risk phenotype resulting in very...
9.
Zeka F, Decock A, Van Goethem A, Vanderheyden K, Demuynck F, Lammens T, et al.
JCI Insight . 2018 Dec; 3(23). PMID: 30518699
In this study, the circulating miRNome from diagnostic neuroblastoma serum was assessed for identification of noninvasive biomarkers with potential in monitoring metastatic disease. After determining the circulating neuroblastoma miRNome, 743...
10.
Cattoir L, Van Hoecke F, Van Maerken T, Nys E, Ryckaert I, De Boulle M, et al.
J Clin Virol . 2018 Mar; 103:8-11. PMID: 29602096
Background: Hepatitis E virus (HEV) infection is increasingly recognized as a cause of hepatitis in developed countries. A high HEV IgG seroprevalence in humans and pigs is reported as well...