Tom S Wehrman
Overview
Explore the profile of Tom S Wehrman including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
542
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0
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Recent Articles
11.
A novel enzyme complementation-based assay for monitoring G-protein-coupled receptor internalization
Hammer M, Wehrman T, Blau H
FASEB J
. 2007 Oct;
21(14):3827-34.
PMID: 17942829
G-protein-coupled receptor (GPCR) signaling is involved in a wide range of physiological processes and diseases, and around one-half of currently used drugs target GPCRs. Assays for the signaling of GPCRs...
12.
von Degenfeld G, Wehrman T, Hammer M, Blau H
FASEB J
. 2007 Oct;
21(14):3819-26.
PMID: 17942828
G-protein coupled receptors (GPCRs) are a versatile and ubiquitous family of membrane receptors that transmit extracellular signals to mammalian cells and constitute the most important class of drug targets. Yet,...
13.
Sen G, Wehrman T, Blau H
Differentiation
. 2005 Sep;
73(6):287-93.
PMID: 16138829
RNA interference constitutes a major means of eliminating mRNAs, yet how the small interfering RNAs (siRNA) within the RNA-induced silencing complex (RISC) finds its homologous target in the cell remains...
14.
Wehrman T, Casipit C, Gewertz N, Blau H
Nat Methods
. 2005 Jun;
2(7):521-7.
PMID: 15973423
Fundamental to eukaryotic cell signaling is the regulation of protein function by directed localization. Detection of these events has been largely qualitative owing to the limitations of existing technologies. Here...
15.
Sen G, Wehrman T, Myers J, Blau H
Nat Genet
. 2004 Jan;
36(2):183-9.
PMID: 14704668
Small interfering RNA (siRNA) technology facilitates the study of loss of gene function in mammalian cells and animal models, but generating multiple siRNA vectors using oligonucleotides is slow, inefficient and...