Todd Lencz
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Explore the profile of Todd Lencz including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Rabe F, Smigielski L, Georgiadis F, Kallen N, Omlor W, Kirschner M, et al.
medRxiv
. 2024 Apr;
PMID: 38633770
The human retina is part of the central nervous system and can be easily and non-invasively imaged with optical coherence tomography. While imaging the retina may provide insights on central...
12.
Gallego J, McNamara R, Blanco E, Castaneda S, Jimenez L, Alvarez-Lesmes S, et al.
Psychiatry Res
. 2024 Mar;
335:115871.
PMID: 38547600
Abnormalities in immune function have been described in schizophrenia but few studies have investigated cytokines in cerebrospinal fluid (CSF) and their correlation with blood levels. In this cross-sectional study, cytokines...
13.
Tian R, Ge T, Kweon H, Rocha D, Lam M, Liu J, et al.
Nat Commun
. 2024 Feb;
15(1):1755.
PMID: 38409228
Nearly two hundred common-variant depression risk loci have been identified by genome-wide association studies (GWAS). However, the impact of rare coding variants on depression remains poorly understood. Here, we present...
14.
Bhattacharyya U, John J, Lam M, Fisher J, Sun B, Baird D, et al.
medRxiv
. 2024 Jan;
PMID: 38293198
Background: Research on peripheral (e.g., blood-based) biomarkers for psychiatric illness has typically been low-throughput in terms of both the number of subjects and the range of assays performed. Moreover, traditional...
15.
Voineskos A, Hawco C, Neufeld N, Turner J, Ameis S, Anticevic A, et al.
World Psychiatry
. 2024 Jan;
23(1):26-51.
PMID: 38214624
Functional neuroimaging emerged with great promise and has provided fundamental insights into the neurobiology of schizophrenia. However, it has faced challenges and criticisms, most notably a lack of clinical translation....
16.
Rubio J, Lencz T, Cao H, Kraguljac N, Dhamala E, Homan P, et al.
Mol Psychiatry
. 2024 Jan;
29(4):929-938.
PMID: 38177349
To bring biomarkers closer to clinical application, they should be generalizable, reliable, and maintain performance within the constraints of routine clinical conditions. The functional striatal abnormalities (FSA), is among the...
17.
Levey D, Galimberti M, Deak J, Wendt F, Bhattacharya A, Koller D, et al.
Nat Genet
. 2023 Nov;
55(12):2094-2103.
PMID: 37985822
As recreational use of cannabis is being decriminalized in many places and medical use widely sanctioned, there are growing concerns about increases in cannabis use disorder (CanUD), which is associated...
18.
Lim K, Yee J, See Y, Ng B, Zheng S, Tang C, et al.
Asian J Psychiatr
. 2023 Nov;
90:103826.
PMID: 37944474
Background: Treatment-resistant schizophrenia (TRS) affects a substantial proportion of patients who do not respond adequately to antipsychotic medications, yet the underlying biological mechanism remains poorly understood. This study investigates the...
19.
Barlevy D, Cenolli I, Campbell T, Furrer R, Mukherjee M, Kostick-Quenet K, et al.
medRxiv
. 2023 Oct;
PMID: 37873214
Objective: To explore and compare the perspectives of clinicians and patients on polygenic embryo screening. Design: Qualitative. Subjects: Fifty-three participants: 27 reproductive endocrinology and infertility specialists and 26 patients currently...
20.
Cao H, Lencz T, Gallego J, Rubio J, John M, Barber A, et al.
Am J Psychiatry
. 2023 Aug;
180(11):827-835.
PMID: 37644811
Objective: Identification of robust biomarkers that predict individualized response to antipsychotic treatment at the early stage of psychotic disorders remains a challenge in precision psychiatry. The aim of this study...