Todd Fallesen
Overview
Explore the profile of Todd Fallesen including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
212
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Recent Articles
1.
Brumm A, McCarthy A, Gerri C, Fallesen T, Woods L, McMahon R, et al.
Dev Cell
. 2024 Nov;
60(2):174-185.e5.
PMID: 39561779
The human blastocyst contains the pluripotent epiblast from which human embryonic stem cells (hESCs) can be derived. ACTIVIN/NODAL signaling maintains expression of the transcription factor NANOG and in vitro propagation...
2.
Huerga Encabo H, Aramburu I, Garcia-Albornoz M, Piganeau M, Wood H, Song A, et al.
Cell Stem Cell
. 2023 Jun;
30(6):781-799.e9.
PMID: 37267914
Somatic mutations commonly occur in hematopoietic stem cells (HSCs). Some mutant clones outgrow through clonal hematopoiesis (CH) and produce mutated immune progenies shaping host immunity. Individuals with CH are asymptomatic...
3.
Kakui Y, Barrington C, Kusano Y, Thadani R, Fallesen T, Hirota T, et al.
Cell Rep
. 2022 Dec;
41(10):111753.
PMID: 36476849
Mitotic chromosomes in different organisms adopt various dimensions. What defines these dimensions is scarcely understood. Here, we compare mitotic chromosomes in budding and fission yeasts harboring similarly sized genomes distributed...
4.
Lea R, McCarthy A, Boeing S, Fallesen T, Elder K, Snell P, et al.
Development
. 2021 Oct;
148(22).
PMID: 34661235
Current knowledge of the transcriptional regulation of human pluripotency is incomplete, with lack of interspecies conservation observed. Single-cell transcriptomics analysis of human embryos previously enabled us to identify transcription factors,...
5.
Dowbaj A, Jenkins R, Williamson D, Heddleston J, Ciccarelli A, Fallesen T, et al.
J Cell Sci
. 2021 Jun;
134(13).
PMID: 34060624
The shuttling of transcription factors and transcriptional regulators into and out of the nucleus is central to the regulation of many biological processes. Here we describe a new method for...
6.
Amarteifio S, Fallesen T, Pruessner G, Sena G
Plant Methods
. 2021 Mar;
17(1):25.
PMID: 33685468
Background: Particle-tracking in 3D is an indispensable computational tool to extract critical information on dynamical processes from raw time-lapse imaging. This is particularly true with in vivo time-lapse fluorescence imaging...
7.
Obata Y, Castano A, Boeing S, Bon-Frauches A, Fung C, Fallesen T, et al.
Nature
. 2020 Feb;
578(7794):284-289.
PMID: 32025031
Neural control of the function of visceral organs is essential for homeostasis and health. Intestinal peristalsis is critical for digestive physiology and host defence, and is often dysregulated in gastrointestinal...
8.
Fallesen T, Roostalu J, Duellberg C, Pruessner G, Surrey T
Biophys J
. 2017 Nov;
113(9):2055-2067.
PMID: 29117528
Most kinesin motors move in only one direction along microtubules. Members of the kinesin-5 subfamily were initially described as unidirectional plus-end-directed motors and shown to produce piconewton forces. However, some...
9.
Fallesen T, Hill D, Steen M, Macosko J, Bonin K, Holzwarth G
Rev Sci Instrum
. 2010 Aug;
81(7):074303.
PMID: 20687745
Here we report construction of a simple electromagnet with novel polepieces which apply a spatially uniform force to superparamagnetic beads in an optical microscope. The wedge-shaped gap was designed to...