Todd B Cole
Overview
Explore the profile of Todd B Cole including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
6
Citations
144
Followers
0
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Recent Articles
1.
McGaraughty S, Davis-Taber R, Zhu C, Cole T, Nikkel A, Chhaya M, et al.
J Am Soc Nephrol
. 2017 Aug;
28(12):3616-3626.
PMID: 28827403
Targeted delivery of a therapeutic agent to a site of pathology to ameliorate disease while limiting exposure at undesired tissues is an aspirational treatment scenario. Targeting diseased kidneys for pharmacologic...
2.
Reilly E, Phillips A, Buchanan F, Kingsbury G, Zhang Y, Meulbroek J, et al.
Mol Cancer Ther
. 2015 Mar;
14(5):1141-51.
PMID: 25731184
Despite clinical efficacy, current approved agents targeting EGFR are associated with on-target toxicities as a consequence of disrupting normal EGFR function. MAb 806 is a novel EGFR antibody that selectively...
3.
Mudd S, Holich K, Voorbach M, Cole T, Reuter D, Tapang P, et al.
Mol Imaging Biol
. 2011 Dec;
14(5):617-24.
PMID: 22167582
Purpose: Longitudinal changes of 3'-[(18) F]fluoro-3'-deoxythymidine (FLT) and 2-deoxy-2-[(18) F]fluoro-D-glucose (FDG) in response to irinotecan therapy in an animal model of colorectal cancer were compared. Procedures: SCID/CB-17 mice with HCT116...
4.
Luo Y, Jiang F, Cole T, Hradil V, Reuter D, Chakravartty A, et al.
Cancer Chemother Pharmacol
. 2011 Nov;
69(4):911-21.
PMID: 22080168
Tyrosine kinase inhibitors represent a class of targeted therapy that has proven to be successful for cancer treatment. Linifanib is a novel, orally active multi-targeted receptor tyrosine kinase (RTK) inhibitor...
5.
Sakoglu U, Upadhyay J, Chin C, Chandran P, Baker S, Cole T, et al.
Biochem Pharmacol
. 2011 Jan;
81(12):1374-87.
PMID: 21219879
During the last two decades, functional neuroimaging technology, especially functional magnetic resonance imaging (fMRI), has improved tremendously, with new attention towards resting-state functional connectivity of the brain. This development has...
6.
Luo F, Rustay N, Ebert U, Hradil V, Cole T, Llano D, et al.
Neurobiol Aging
. 2010 Oct;
33(5):933-44.
PMID: 20961663
With 90% of neuroscience clinical trials failing to see efficacy, there is a clear need for the development of disease biomarkers that can improve the ability to predict human Alzheimer's...