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Toby Starr

Explore the profile of Toby Starr including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 263
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Recent Articles
1.
Gutenkunst R, Coombs D, Starr T, Dustin M, Goldstein B
PLoS One . 2011 Jun; 6(5):e19701. PMID: 21629715
A promising direction in drug development is to exploit the ability of natural killer cells to kill antibody-labeled target cells. Monoclonal antibodies and drugs designed to elicit this effect typically...
2.
Milstein O, Tseng S, Starr T, Llodra J, Nans A, Liu M, et al.
J Biol Chem . 2008 Oct; 283(49):34414-22. PMID: 18826951
The relationship between intermembrane spacing, adhesion efficiency, and lateral organization of adhesion receptors has not been established for any adhesion system. We have utilized the CD2 ligand CD48 with two...
3.
Vasiliver-Shamis G, Tuen M, Wu T, Starr T, Cameron T, Thomson R, et al.
J Virol . 2008 Jul; 82(19):9445-57. PMID: 18632854
Human immunodeficiency virus type 1 (HIV-1)-infected T cells form a virological synapse with noninfected CD4(+) T cells in order to efficiently transfer HIV-1 virions from cell to cell. The virological...
4.
Dustin M, Starr T, Varma R, Thomas V
Curr Protoc Immunol . 2008 Apr; Chapter 18:18.13.1-18.13.35. PMID: 18432988
Supported planar bilayers have been used in immunology research for over 25 years, including in the initial demonstrations of MHC-peptide complex functional activity and adhesion molecule activity. More recent modifications...
5.
DeMond A, Mossman K, Starr T, Dustin M, Groves J
Biophys J . 2008 Jan; 94(8):3286-92. PMID: 18199675
Recognition of peptide antigen by T cells involves coordinated movement of T cell receptors (TCRs) along with other costimulatory and signaling molecules. The spatially organized configurations that result are collectively...
6.
Dustin M, Starr T, Coombs D, Majeau G, Meier W, Hochman P, et al.
J Biol Chem . 2007 Oct; 282(48):34748-57. PMID: 17911103
Alefacept is a chimeric protein combining CD58 immunoglobulin-like domain 1 with human IgG1 Fc. Alefacept mediates adhesion by bridging CD2 on T cells to activating Fc receptors on effector cells,...
7.
DeMond A, Starr T, Dustin M, Groves J
J Am Chem Soc . 2006 Nov; 128(48):15354-5. PMID: 17131984
The immunological synapse is a specialized intercellular junction between a T cell and a target cell that orchestrates the engagement of receptors and ligands in space and time as a...