Tobias Wijshake
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Explore the profile of Tobias Wijshake including associated specialties, affiliations and a list of published articles.
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13
Citations
2663
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0
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Recent Articles
1.
Wijshake T, Rose 3rd J, Wang J, Zielke J, Marlar-Pavey M, Chen W, et al.
J Immunol
. 2024 Jan;
212(4):607-616.
PMID: 38169327
Helminth infections are common in animals. However, the impact of a helminth infection on the function of hematopoietic stem cells (HSCs) and other hematopoietic cells has not been comprehensively defined....
2.
Wijshake T, Wang J, Rose 3rd J, Marlar-Pavey M, Collins 3rd J, Agathocleous M
bioRxiv
. 2023 Feb;
PMID: 36798229
Helminth infections are common in animals. However, the impact of a helminth infection on the function of hematopoietic stem cells (HSCs) and other hematopoietic cells has not been comprehensively defined....
3.
Riedlinger T, Dommerholt M, Wijshake T, Kruit J, Huijkman N, Dekker D, et al.
Biochim Biophys Acta Mol Cell Res
. 2021 Mar;
1868(6):119008.
PMID: 33715857
No abstract available.
4.
Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(5).
PMID: 33495338
Beclin 1, an autophagy and haploinsufficient tumor-suppressor protein, is frequently monoallelically deleted in breast and ovarian cancers. However, the precise mechanisms by which Beclin 1 inhibits tumor growth remain largely...
5.
Liu Y, Nguyen P, Wang X, Zhao Y, Meacham C, Zou Z, et al.
Nature
. 2020 Feb;
578(7796):605-609.
PMID: 32051584
The activation of adenosine monophosphate-activated protein kinase (AMPK) in skeletal muscle coordinates systemic metabolic responses to exercise. Autophagy-a lysosomal degradation pathway that maintains cellular homeostasis-is upregulated during exercise, and a...
6.
Riedlinger T, Dommerholt M, Wijshake T, Kruit J, Huijkman N, Dekker D, et al.
Biochim Biophys Acta Mol Cell Res
. 2017 Jul;
1864(10):1785-1798.
PMID: 28723419
The NF-κB family of transcription factors is essential for an effective immune response, but also controls cell metabolism, proliferation and apoptosis. Its broad relevance and the high connectivity to diverse...
7.
Childs B, Baker D, Wijshake T, Conover C, Campisi J, van Deursen J
Science
. 2016 Oct;
354(6311):472-477.
PMID: 27789842
Advanced atherosclerotic lesions contain senescent cells, but the role of these cells in atherogenesis remains unclear. Using transgenic and pharmacological approaches to eliminate senescent cells in atherosclerosis-prone low-density lipoprotein receptor-deficient...
8.
Bartuzi P, Wijshake T, Dekker D, Fedoseienko A, Kloosterhuis N, Youssef S, et al.
Biochim Biophys Acta
. 2014 Jul;
1842(11):2257-65.
PMID: 25072958
The transcription factor NF-κB plays a critical role in the inflammatory response and it has been implicated in various diseases, including non-alcoholic fatty liver disease (NAFLD). Although transient NF-κB activation...
9.
Wijshake T, Baker D, van de Sluis B
Biochim Biophys Acta
. 2014 May;
1842(10):1942-1950.
PMID: 24794718
Mouse transgenesis has been instrumental in determining the function of genes in the pathophysiology of human diseases and modification of genes by homologous recombination in mouse embryonic stem cells remains...
10.
Wijshake T, Malureanu L, Baker D, Jeganathan K, van de Sluis B, van Deursen J
PLoS Genet
. 2013 Jan;
8(12):e1003138.
PMID: 23300461
Mosaic Variegated Aneuploidy (MVA) syndrome is a rare autosomal recessive disorder characterized by inaccurate chromosome segregation and high rates of near-diploid aneuploidy. Children with MVA syndrome die at an early...