Tobias Schiergens
Overview
Explore the profile of Tobias Schiergens including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
100
Followers
0
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Recent Articles
1.
Schockel L, Woischke C, Surendran S, Michl M, Schiergens T, Holscher A, et al.
BMC Cancer
. 2024 Feb;
24(1):234.
PMID: 38378472
Background: Peroxisome proliferator-activated receptor gamma (PPARG) is a member of the nuclear receptor family. It is involved in the regulation of adipogenesis, lipid metabolism, insulin sensitivity, vascular homeostasis and inflammation....
2.
Zimny S, Koob D, Li J, Wimmer R, Schiergens T, Nagel J, et al.
Cells
. 2022 Aug;
11(15).
PMID: 35954188
Bile salts accumulating during cholestatic liver disease are believed to promote liver fibrosis. We have recently shown that chenodeoxycholate (CDC) induces expansion of hepatic stellate cells (HSCs) in vivo, thereby...
3.
Kuhn F, Schardey J, Wirth U, Schiergens T, Crispin A, Beger N, et al.
Int J Colorectal Dis
. 2021 Nov;
37(2):283-292.
PMID: 34817647
Background: During the last two decades, vacuum-assisted wound therapy has been successfully transferred to an endoscopic treatment approach of various upper and lower gastrointestinal leaks called endoscopic vacuum therapy (EVT)....
4.
Lin T, Wang S, Munker S, Jung K, Macias-Rodriguez R, Ruiz-Margain A, et al.
Hepatology
. 2021 Aug;
75(2):322-337.
PMID: 34435364
Background And Aims: In patients with acute liver failure (ALF) who suffer from massive hepatocyte loss, liver progenitor cells (LPCs) take over key hepatocyte functions, which ultimately determines survival. This...
5.
Vangala D, Ladigan S, Liffers S, Noseir S, Maghnouj A, Gotze T, et al.
Genome Med
. 2021 Jul;
13(1):116.
PMID: 34271981
Background: The development of secondary resistance (SR) in metastatic colorectal cancer (mCRC) treated with anti-epidermal growth factor receptor (anti-EGFR) antibodies is not fully understood at the molecular level. Here we...
6.
Hohenester S, Kanitz V, Schiergens T, Einer C, Nagel J, Wimmer R, et al.
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33202693
Non-alcoholic fatty liver disease (NAFLD) is rising in prevalence, and a better pathophysiologic understanding of the transition to its inflammatory phenotype (NASH) is key to the development of effective therapies....
7.
Wolf S, Lauseker M, Schiergens T, Wirth U, Drefs M, Renz B, et al.
Transpl Infect Dis
. 2020 Feb;
22(3):e13267.
PMID: 32072714
Background: Side effects of the immunosuppressive therapy after solid organ transplantation are well known. Recently, significant benefits were shown for mTOR-Is with respect to certain viral infections in comparison with...
8.
Ryll M, Bucher J, Drefs M, Bosch F, Kumaraswami K, Schiergens T, et al.
J Vis Exp
. 2019 Nov;
(153).
PMID: 31736501
With the introduction of powerful immunosuppressive protocols, distinct advances are possible in the prevention and therapy of acute rejection episodes. However, only minor improvement in the long-term results of transplanted...
9.
Schwandner F, Klimars U, Gock M, Schiffmann L, Witte M, Schiergens T, et al.
J Gastrointest Surg
. 2019 Mar;
24(2):411-417.
PMID: 30825120
Background: A defunctioning stoma can become necessary in a relevant number of patients undergoing gastrointestinal surgery. As a matter of course, patients seek an early closure of the stoma. However,...
10.
Heiliger C, Piecuch J, Frank A, Andrade D, von Ehrlich-Treuenstatt V, Schiergens T, et al.
Minim Invasive Ther Allied Technol
. 2018 Nov;
28(6):321-325.
PMID: 30442057
In this pilot animal study we examined whether it is possible to visualize the embryonal resection layers by using intraarterial indocyanine green (ICG) staining when performing total mesorectal excision (TME)...