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Tobias Mourier

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Articles 55
Citations 2056
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Recent Articles
1.
Haidar M, Mourier T, Salunke R, Kaushik A, Ben-Rached F, Mfarrej S, et al.
Biomed J . 2025 Jan; 100828. PMID: 39798869
Theileria parasites are known to induce the transformation of host bovine leukocytes, involved in rapid proliferation, evasion from apoptotic mechanisms, and increased dissemination. In this study, we reveal the involvement...
2.
Klinger C, Jimenez-Ruiz E, Mourier T, Klingl A, Lemgruber L, Pain A, et al.
Cell Rep . 2024 Feb; 43(2):113740. PMID: 38363682
The organelle paralogy hypothesis (OPH) aims to explain the evolution of non-endosymbiotically derived organelles. It predicts that lineage-specific pathways or organelles should result when identity-encoding membrane-trafficking components duplicate and co-evolve....
3.
Subudhi A, Green J, Satyam R, Salunke R, Lenz T, Shuaib M, et al.
Nat Microbiol . 2023 Oct; 8(11):2154-2169. PMID: 37884813
Malaria-associated pathogenesis such as parasite invasion, egress, host cell remodelling and antigenic variation requires concerted action by many proteins, but the molecular regulation is poorly understood. Here we have characterized...
4.
Shuaib M, Adroub S, Mourier T, Mfarrej S, Zhang H, Esau L, et al.
Genome Med . 2023 Jul; 15(1):54. PMID: 37475040
Background: The excessive inflammatory responses provoked by SARS-CoV-2 infection are critical factors affecting the severity and mortality of COVID-19. Previous work found that two adjacent co-occurring mutations R203K and G204R...
5.
Subudhi A, Green J, Satyam R, Lenz T, Salunke R, Shuaib M, et al.
bioRxiv . 2023 Jun; PMID: 37293082
Malaria pathogenicity results from the parasite's ability to invade, multiply within and then egress from the host red blood cell (RBC). Infected RBCs are remodeled, expressing antigenic variant proteins (such...
6.
Haidar M, Tajeri S, Momeux L, Mourier T, Ben-Rached F, Mfarrej S, et al.
mSphere . 2023 Feb; 8(2):e0052622. PMID: 36847534
MicroRNAs (miRNAs) are small noncoding RNAs that can play critical roles in regulating various cellular processes, including during many parasitic infections. Here, we report a regulatory role for miR-34c-3p in...
7.
Alshukairi A, Aldabbagh Y, Adroub S, Mourier T, Abumelha K, Albishi G, et al.
J Epidemiol Glob Health . 2023 Jan; 13(1):47-54. PMID: 36626091
The outcome of transplant recipients is variable depending on the study population, vaccination status and COVID-19 variants. Our aim was to study the impact of Omicron subvariants on the mortality...
8.
Tajeri S, Momeux L, Saintpierre B, Mfarrej S, Chapple A, Mourier T, et al.
Sci Rep . 2022 Jul; 12(1):12710. PMID: 35882887
A fungal metabolite, FR235222, specifically inhibits a histone deacetylase of the apicomplexan parasite Toxoplasma gondii and TgHDAC3 has emerged as a key factor regulating developmental stage transition in this species....
9.
Mourier T, Shuaib M, Hala S, Mfarrej S, Alofi F, Naeem R, et al.
Nat Commun . 2022 Feb; 13(1):601. PMID: 35105893
Monitoring SARS-CoV-2 spread and evolution through genome sequencing is essential in handling the COVID-19 pandemic. Here, we sequenced 892 SARS-CoV-2 genomes collected from patients in Saudi Arabia from March to...
10.
Mourier T, de Alvarenga D, Kaushik A, Pina-Costa A, Douvropoulou O, Guan Q, et al.
BMC Biol . 2021 Oct; 19(1):219. PMID: 34592986
Background: Plasmodium simium, a malaria parasite of non-human primates (NHP), was recently shown to cause zoonotic infections in humans in Brazil. We sequenced the P. simium genome to investigate its...