Tina M Kilts
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Explore the profile of Tina M Kilts including associated specialties, affiliations and a list of published articles.
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23
Citations
1234
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Recent Articles
1.
Shainer R, Kram V, Kilts T, Li L, Doyle A, Shainer I, et al.
Front Physiol
. 2023 Mar;
14:1119368.
PMID: 36875017
Endochondral bone development and regeneration relies on activation and proliferation of periosteum derived-cells (PDCs). Biglycan (Bgn), a small proteoglycan found in extracellular matrix, is known to be expressed in bone...
2.
Komori T, Pham H, Jani P, Perry S, Wang Y, Kilts T, et al.
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430826
Many studies have been conducted to elucidate the role of Type VI collagen in muscle and tendon, however, its role in oral tissues remains unclear. In this study, an α2(VI)...
3.
Chandler R, Di Pasquale G, Sloan J, McCoy S, Hubbard B, Kilts T, et al.
Mol Ther Methods Clin Dev
. 2022 Oct;
27:61-72.
PMID: 36186952
Methylmalonic acidemia (MMA) is a severe and potentially lethal autosomal recessive inborn error of metabolism most frequently caused by mutations in the methylmalonyl-CoA mutase () gene. Proof-of-concept adeno-associated virus (AAV)...
4.
Komori T, Ji Y, Pham H, Jani P, Kilts T, Kram V, et al.
JBMR Plus
. 2022 May;
6(5):e10617.
PMID: 35509631
For many years there has been a keen interest in developing regenerative treatment for temporomandibular joint-osteoarthritis (TMJ-OA). Currently, there is no consensus treatment due to the limited self-healing ability of...
5.
Leiphart R, Pham H, Harvey T, Komori T, Kilts T, Shetye S, et al.
Matrix Biol Plus
. 2022 Jan;
13:100099.
PMID: 35036900
Tendon is a vital musculoskeletal tissue that is prone to degeneration. Proper tendon maintenance requires complex interactions between extracellular matrix components that remain poorly understood. Collagen VI and biglycan are...
6.
Kram V, Jani P, Kilts T, Li L, Chu E, Young M
J Struct Biol
. 2020 Sep;
212(3):107627.
PMID: 32950603
Biglycan (Bgn) and Fibromodulin (Fmod) are small leucine rich proteoglycans (SLRPs) which are abundant in the extra-cellular matrix (ECM) of mineralized tissues. We have previously generated a Bgn/Fmod double knock-out...
7.
Pham H, Kram V, Dar Q, Komori T, Ji Y, Mohassel P, et al.
Sci Rep
. 2020 Aug;
10(1):13749.
PMID: 32792616
Type VI collagen is well known for its role in muscular disorders, however its function in bone is still not well understood. To examine its role in bone we analyzed...
8.
Stratman A, Farrelly O, Mikelis C, Miller M, Wang Z, Pham V, et al.
Nat Commun
. 2020 Mar;
11(1):1204.
PMID: 32139674
Anti-angiogenic therapies have generated significant interest for their potential to combat tumor growth. However, tumor overproduction of pro-angiogenic ligands can overcome these therapies, hampering success of this approach. To circumvent...
9.
Ono M, Masaki A, Maeda A, Kilts T, Hara E, Komori T, et al.
Matrix Biol
. 2018 Jan;
68-69:533-546.
PMID: 29330021
Understanding the mechanisms that control cutaneous wound healing is crucial to successfully manage repair of damaged skin. The goal of the current study was to uncover novel extracellular matrix (ECM)...
10.
Kram V, Kilts T, Bhattacharyya N, Li L, Young M
Sci Rep
. 2017 Oct;
7(1):12627.
PMID: 28974711
Biglycan (Bgn) and Fibromodulin (Fmod) are subtypes of the small leucine-rich family of proteoglycans (SLRP). In this study we examined the skeletal phenotype of BgnFmod double knockout (BgnFmod KO) mice...