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Tina C Legler

Explore the profile of Tina C Legler including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 1356
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Recent Articles
1.
McDermott G, Do D, Litterst C, Maar D, Hindson C, Steenblock E, et al.
Anal Chem . 2013 Nov; 85(23):11619-27. PMID: 24180464
Two years ago, we described the first droplet digital PCR (ddPCR) system aimed at empowering all researchers with a tool that removes the substantial uncertainties associated with using the analogue...
2.
Beller H, Zhou P, Legler T, Chakicherla A, Kane S, Letain T, et al.
Front Microbiol . 2013 Sep; 4:249. PMID: 24065960
Thiobacillus denitrificans is a chemolithoautotrophic bacterium capable of anaerobic, nitrate-dependent U(IV) and Fe(II) oxidation, both of which can strongly influence the long-term efficacy of in situ reductive immobilization of uranium...
3.
Beller H, Legler T, Kane S
Methods Mol Biol . 2012 May; 881:99-136. PMID: 22639212
Chemolithoautotrophic bacteria can be of industrial and environmental importance, but they present a challenge for systems biology studies, as their central metabolism deviates from that of model organisms and there...
4.
Hindson B, Ness K, Masquelier D, Belgrader P, Heredia N, Makarewicz A, et al.
Anal Chem . 2011 Nov; 83(22):8604-10. PMID: 22035192
Digital PCR enables the absolute quantitation of nucleic acids in a sample. The lack of scalable and practical technologies for digital PCR implementation has hampered the widespread adoption of this...
5.
Beller H, Kane S, Legler T, McKelvie J, Lollar B, Pearson F, et al.
Environ Sci Technol . 2008 Sep; 42(16):6065-72. PMID: 18767667
A controlled-release study conducted at Vandenberg Air Force Base involved the injection of anaerobic groundwater amended with benzene, toluene, and o-xylene (BToX; 1-3 mg/L each) in two parallel lanes: lane...
6.
Beller H, Legler T, Bourguet F, Letain T, Kane S, Coleman M
Biodegradation . 2008 May; 20(1):45-53. PMID: 18470655
Anaerobic, bacterial reduction of water-soluble U(VI) complexes to the poorly soluble U(IV) mineral uraninite has been intensively studied as a strategy for in situ remediation of uranium-contaminated groundwater. A novel...
7.
Hristova K, Schmidt R, Chakicherla A, Legler T, Wu J, Chain P, et al.
Appl Environ Microbiol . 2007 Sep; 73(22):7347-57. PMID: 17890343
High-density whole-genome cDNA microarrays were used to investigate substrate-dependent gene expression of Methylibium petroleiphilum PM1, one of the best-characterized aerobic methyl tert-butyl ether (MTBE)-degrading bacteria. Differential gene expression profiling was...
8.
Letain T, Kane S, Legler T, Salazar E, Agron P, Beller H
Appl Environ Microbiol . 2007 Mar; 73(10):3265-71. PMID: 17337560
Thiobacillus denitrificans is a widespread, chemolithoautotrophic bacterium with an unusual and environmentally relevant metabolic repertoire, which includes its ability to couple denitrification to sulfur compound oxidation; to catalyze anaerobic, nitrate-dependent...
9.
Kane S, Chakicherla A, Chain P, Schmidt R, Shin M, Legler T, et al.
J Bacteriol . 2006 Dec; 189(5):1931-45. PMID: 17158667
Methylibium petroleiphilum PM1 is a methylotroph distinguished by its ability to completely metabolize the fuel oxygenate methyl tert-butyl ether (MTBE). Strain PM1 also degrades aromatic (benzene, toluene, and xylene) and...
10.
Beller H, Letain T, Chakicherla A, Kane S, Legler T, Coleman M
J Bacteriol . 2006 Sep; 188(19):7005-15. PMID: 16980503
Thiobacillus denitrificans is one of the few known obligate chemolithoautotrophic bacteria capable of energetically coupling thiosulfate oxidation to denitrification as well as aerobic respiration. As very little is known about...