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Timothy S Owen

Explore the profile of Timothy S Owen including associated specialties, affiliations and a list of published articles. Areas
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1.
Zhang X, Xu Z, Moumin D, Ciulla D, Owen T, Mancusi R, et al.
Bioconjug Chem . 2019 Oct; 30(11):2799-2804. PMID: 31600061
Hedgehog (Hh) precursor proteins contain an autoprocessing domain called HhC whose native function is protein cleavage and C-terminal glycine sterylation. The transformation catalyzed by HhC occurs in from a precursor...
2.
Owen T, Salom D, Sun W, Palczewski K
Biochemistry . 2018 Jan; 57(6):1022-1030. PMID: 29320632
Three types of cone cells exist in the human retina, each containing a different pigment responsible for the initial step of phototransduction. These pigments are distinguished by their specific absorbance...
3.
Owen T, Ngoje G, Lageman T, Bordeau B, Belfort M, Callahan B
Anal Biochem . 2015 Jun; 488:1-5. PMID: 26095399
Hedgehog (Hh) proteins function in cell/cell signaling processes linked to human embryo development and the progression of several types of cancer. Here, we describe an optical assay of hedgehog cholesterolysis,...
4.
Owen T, Xie X, Laraway B, Ngoje G, Wang C, Callahan B
Chembiochem . 2014 Nov; 16(1):55-8. PMID: 25418613
Hedgehog proteins, signaling molecules implicated in human embryo development and cancer, can be inhibited at the stage of autoprocessing by the trivalent arsenical phenyl arsine oxide (PhAs(III) ). The interaction...