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Timothy R Lex

Explore the profile of Timothy R Lex including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 27
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Recent Articles
1.
Lex T, Rodriguez J, Zhang L, Jiang W, Gao Z
AAPS J . 2022 Mar; 24(2):40. PMID: 35277760
In vitro dissolution testing is widely used to mimic and predict in vivo performance of oral drug products in the gastrointestinal (GI) tract. This literature review assesses the current in...
2.
Lex T, Brummel B, Attia M, Giambalvo L, Lee K, Van Horn B, et al.
Sci Rep . 2020 Feb; 10(1):1508. PMID: 32001741
Synthetic materials exhibiting contrast imaging properties have become vital to the field of biomedical imaging. However, polymeric biomaterials are lacking imaging contrast properties for deep tissue imaging. This report details...
3.
Narangoda C, Kakeshpour T, Lex T, Redden B, Moore M, Frank E, et al.
J Org Chem . 2019 Jul; 84(15):9734-9743. PMID: 31295401
The α-oxidized thioimidates are useful bidentate ligands and are important motifs in pharmaceuticals, pesticides, and fungicides. Despite their broad utility, a direct route for their synthesis has been elusive. Herein,...
4.
Narangoda C, Lex T, Moore M, McMillen C, Kitaygorodskiy A, Jackson J, et al.
Org Lett . 2018 Dec; 20(24):8009-8013. PMID: 30525696
A formal [2 + 2] cycloaddition of 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) with electron-rich alkynyl sulfides and selenides is described. These investigations provide a convenient method to access diazacyclobutenes in good yield while...
5.
Attia M, Brummel B, Lex T, Van Horn B, Whitehead D, Alexis F
Adv Healthc Mater . 2018 Oct; 7(22):e1800798. PMID: 30295005
Several synthetic materials exhibiting contrast imaging properties have become vital to the field of biomedical imaging. Polymeric biomaterials and metals are commonly used imaging agents and can assist in the...
6.
Lex T, Swasy M, Whitehead D
J Org Chem . 2015 Nov; 80(24):12234-43. PMID: 26599392
A series of rate studies were conducted to evaluate the steric and electronic properties that govern the reactivity of iodoarene amide catalysts in the α-oxytosylation of propiophenone. A meta-substituted benzamide...