Timothy R Cheek
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Explore the profile of Timothy R Cheek including associated specialties, affiliations and a list of published articles.
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10
Citations
283
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Recent Articles
1.
Whitworth C, Redfern C, Cheek T
Mol Neurobiol
. 2018 May;
56(2):857-872.
PMID: 29802571
Neurogenesis is a complex process leading to the generation of neuronal networks and glial cell types from stem cells or intermediate progenitors. Mapping subcellular and molecular changes accompanying the switch...
2.
Edwards N, Anderson C, Conlon N, Watson A, Hall R, Cheek T, et al.
Cell Mol Life Sci
. 2017 Oct;
75(5):921-938.
PMID: 29058016
Amino acid transporters are essential components of prokaryote and eukaryote cells, possess distinct physiological functions, and differ markedly in substrate specificity. Amino acid transporters can be both drug targets and...
3.
Bell N, Hann V, Redfern C, Cheek T
Biochim Biophys Acta
. 2012 Dec;
1833(3):643-51.
PMID: 23220046
Neuroblastoma cell lines are heterogeneous, comprised of at least three distinct cell phenotypes; neuroblastic N-type cells, non-neuronal substrate-adherent S-type cells and intermediate I-type cells. N- and S-type cell populations were...
4.
Heer R, Clarke N, Rigas A, Cheek T, Pickard R, Leung H
Urology
. 2010 Jun;
76(2):509.e13-20.
PMID: 20546875
Objectives: Animal models have described critical roles for transforming growth factor beta (TGFbeta) isoforms in modulating urinary tract stroma phenotype. TGFbeta3 is of particular interest because it may regulate TGFbeta1...
5.
Tottey S, Waldron K, Firbank S, Reale B, Bessant C, Sato K, et al.
Nature
. 2008 Oct;
455(7216):1138-42.
PMID: 18948958
Metals are needed by at least one-quarter of all proteins. Although metallochaperones insert the correct metal into some proteins, they have not been found for the vast majority, and the...
6.
Sattelle D, Cordova D, Cheek T
Invert Neurosci
. 2008 Aug;
8(3):107-19.
PMID: 18696132
Ryanodine receptors (RyRs) are a distinct class of ligand-gated calcium channels controlling the release of calcium from intracellular stores. They are located on the sarcoplasmic reticulum of muscle and the...
7.
Riddoch F, Brown A, Rowbotham S, Redfern C, Cheek T
Cell Calcium
. 2006 Aug;
41(3):195-206.
PMID: 16914200
We have used single cell fluorescence imaging techniques to examine how functional properties of the caffeine-sensitive Ca(2+) store change during differentiation of a sub-population of caffeine-sensitive SH-SY5Y cells. Application of...
8.
Cheek T, Thorn P
Cell Calcium
. 2006 Jun;
40(3):309-18.
PMID: 16806464
We have combined fluorimetric measurements of the intracellular free Ca(2+) concentration ([Ca(2+)](i)) with the patch clamp technique, to investigate resting Ca(2+) entry in bovine adrenal chromaffin cells. Perfusion with nominally...
9.
Riddoch F, Rowbotham S, Brown A, Redfern C, Cheek T
Cell Calcium
. 2005 Aug;
38(2):111-20.
PMID: 16095688
We have used single cell fluorescence imaging techniques to examine the role that ryanodine receptors play in the stimulus-induced Ca(2+) responses of SH-SY5Y cells. The muscarinic agonist methacholine (1mM) resulted...
10.
Brown A, Riddoch F, Robson A, Redfern C, Cheek T
Biochem J
. 2005 Jan;
388(Pt 3):941-8.
PMID: 15673285
We have investigated effects of neuronal differentiation on hormone-induced Ca2+ entry. Fura-2 fluorescence measurements of undifferentiated SH-SY5Y neuroblastoma cells, stimulated with methacholine, revealed the presence of voltage-operated Ca2+-permeable, Mn2+-impermeable entry...