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Timothy Perk

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Articles 10
Citations 176
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Recent Articles
1.
Levi J, Das M, Vasanawala M, Behl D, Pomper M, Forde P, et al.
J Nucl Med . 2024 Oct; 65(12):1869-1875. PMID: 39448270
Despite the systemic impact of both cancer and the associated immune response, immuno-PET is predominantly centered on assessment of the immune milieu within the tumor microenvironment. The aim of this...
2.
Hazelton J, Kim S, Boerner J, Podgorski I, Perk T, Cackowski F, et al.
Prostate . 2023 May; 83(12):1193-1200. PMID: 37211866
Background: Bone is the most common site of metastases in men with prostate cancer. The objective of this study was to explore potential racial differences in the distribution of tumor...
3.
Chen S, Harmon S, Perk T, Li X, Chen M, Li Y, et al.
Cancer Imaging . 2019 Aug; 19(1):56. PMID: 31420006
Objective: Lung cancer usually presents as a solitary pulmonary nodule (SPN) on diagnostic imaging during the early stages of the disease. Since the early diagnosis of lung cancer is very...
4.
Perk T, Bradshaw T, Chen S, Im H, Cho S, Perlman S, et al.
Phys Med Biol . 2018 Nov; 63(22):225019. PMID: 30457118
Purpose: F-NaF PET/CT imaging of bone metastases is confounded by tracer uptake in benign diseases, such as osteoarthritis. The goal of this work was to develop an automated bone lesion...
5.
Perk T, Chen S, Harmon S, Lin C, Bradshaw T, Perlman S, et al.
Phys Med Biol . 2018 Nov; 63(22):225018. PMID: 30457117
Identification of individual lesions on F-NaF PET bone scans is a time-consuming and often subjective process that makes accurate characterization of disease burden challenging. Current automated methods either underestimate disease...
6.
Chen S, Harmon S, Perk T, Li X, Chen M, Li Y, et al.
Sci Rep . 2017 Aug; 7(1):9370. PMID: 28839156
Lung cancer, the most commonly diagnosed cancer worldwide, usually presents as solid pulmonary nodules (SPNs) on early diagnostic images. Classification of malignant disease at this early timepoint is critical for...
7.
Harmon S, Perk T, Lin C, Eickhoff J, Choyke P, Dahut W, et al.
J Clin Oncol . 2017 Jun; 35(24):2829-2837. PMID: 28654366
Purpose [F]Sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) is a promising radiotracer for quantitative assessment of bone metastases. This study assesses changes in early NaF PET/CT response measures...
8.
Lin C, Bradshaw T, Perk T, Harmon S, Eickhoff J, Jallow N, et al.
J Nucl Med . 2016 Jul; 57(12):1872-1879. PMID: 27445292
Methods: Thirty-five castration-resistant prostate cancer patients with multiple metastases underwent 2 whole-body (test-retest) F-NaF PET/CT scans 3 ± 2 d apart from 1 of 3 imaging sites. A total of...
9.
Muzahir S, Jeraj R, Liu G, Hall L, Rio A, Perk T, et al.
Am J Nucl Med Mol Imaging . 2015 May; 5(2):162-8. PMID: 25973337
Fluorine 18 Sodium Fluoride ((18)F-NaF) (sodium fluoride) PET/CT is a highly sensitive but is a non-specific method for identifying bone metastases. Qualitative scan interpretation using low dose CT for lesion...
10.
Yip S, Perk T, Jeraj R
Phys Med Biol . 2014 Mar; 59(6):1485-99. PMID: 24594843
Accurate registration over multiple scans is necessary to assess treatment response of bone diseases (e.g. metastatic bone lesions). This study aimed to develop and evaluate an articulated registration algorithm for...