Timothy N J Bullock
Overview
Explore the profile of Timothy N J Bullock including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
856
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Recent Articles
1.
Wei X, Qian W, Narasimhan H, Chan T, Liu X, Arish M, et al.
Science
. 2025 Mar;
387(6738):eadq2509.
PMID: 40048515
Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolution and lung repair during severe respiratory...
2.
Stasiak K, Stevens A, Bolte A, Curley C, Perusina Lanfranca M, Lindsay R, et al.
Cancer Immunol Immunother
. 2024 Nov;
74(1):10.
PMID: 39487854
Patients with metastatic brain melanomas (MBM) experience shorter-lasting survival than patients with extracranial metastases, and this is associated with a higher fraction of dysfunctional CD8 T cells. The goal of...
3.
Wessel R, Ageeb N, Obeid J, Mauldin I, Goundry K, Hanson G, et al.
J Immunother Cancer
. 2024 Sep;
12(9).
PMID: 39299754
Background: Major histocompatibility complex class I (MHC-I) loss is frequent in non-small cell lung cancer (NSCLC) rendering tumor cells resistant to T cell lysis. NK cells kill MHC-I-deficient tumor cells,...
4.
Kitelinger L, Thim E, Zipkowitz S, Price R, Bullock T
Cells
. 2024 Aug;
13(16.
PMID: 39195207
For triple-negative breast cancer (TNBC), the most aggressive subset of breast cancer, immune cell infiltrates have prognostic implications. The presence of myeloid-derived suppressor cells supports tumor progression, while tumor-infiltrating lymphocytes...
5.
Wessel R, Ageeb N, Obeid J, Mauldin I, Goundry K, Hanson G, et al.
bioRxiv
. 2024 Jul;
PMID: 38979183
Background: MHC class I (MHC-I) loss is frequent in non-small cell lung cancer (NSCLC) rendering tumor cells resistant to T cell lysis. NK cells kill MHC-I-deficient tumor cells, and although...
6.
Anbaei P, Stevens M, Ball A, Bullock T, Pompano R
Analyst
. 2024 Mar;
149(9):2609-2620.
PMID: 38535830
Cellular metabolism has been closely linked to activation state in cells of the immune system, and the oxygen consumption rate (OCR) in particular serves as a valuable metric for assessing...
7.
Thim E, Kitelinger L, Rivera-Escalera F, Mathew A, Elliott M, Bullock T, et al.
Theranostics
. 2024 Feb;
14(4):1647-1661.
PMID: 38389838
Boiling histotripsy (BH), a mechanical focused ultrasound ablation strategy, can elicit intriguing signatures of anti-tumor immunity. However, the influence of BH on dendritic cell function is unknown, compromising our ability...
8.
9.
Stevens M, Mason F, Bullock T
J Leukoc Biol
. 2023 Dec;
115(4):679-694.
PMID: 38057151
Pharmacological methods for promoting mitochondrial elongation suggest that effector T cells can be altered to support a memory T cell-like metabolic state. Such mitochondrial elongation approaches may enhance the development...
10.
Padilla F, Foley J, Timbie K, Bullock T, Sheybani N
J Immunother Cancer
. 2023 Nov;
11(11).
PMID: 38007236
Focused ultrasound (FUS) is a powerful emerging tool for non-invasive, non-ionizing targeted destruction of tumors. The last two decades have seen a growing body of preclinical and clinical literature supporting...