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Nathan A Franklin

Explore the profile of Nathan A Franklin including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 110
Followers 0
Related Specialties
Emergency Medicine
Allergy & Immunology
General Medicine
Top 10 Co-Authors
Timothy N J Bullock
Hideo Yagita
Martin J Glennie
Han Dong
Drew J Roberts
Lara M Kingeter
Ashley H Ali
Hassan R Mir
Taylor J Bates
Sara H Kift
Published In
J Immunother
US Army Med Dep J
J Immunol
J Orthop Trauma
Eur J Immunol
Affiliations
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Recent Articles
1.
Rapid degradation and non-selectivity of Dakin's solution prevents effectiveness in contaminated musculoskeletal wound models
Mangum L, Franklin N, Garcia G, Akers K, Wenke J
Injury . 2018 Aug; 49(10):1763-1773. PMID: 30104015
Background: Dakin's solution (buffered sodium hypochlorite) has been used as a topical adjunct for the treatment of invasive fungal infections in trauma patients. Prudent use of Dakin's solution (DS) for...
2.
Outcomes of Early Surgical Intervention in Geriatric Proximal Femur Fractures Among Patients Receiving Direct Oral Anticoagulation
Franklin N, Ali A, Hurley R, Mir H, Beltran M
J Orthop Trauma . 2018 Feb; 32(6):269-273. PMID: 29432317
Objective: To evaluate the prehospital use of direct oral anticoagulant (DOAC) agents on the outcomes of early surgical fixation of a geriatric hip fracture. Design: Case control study. Setting: Two...
3.
Characteristics of US combat veterans (2001-2011) who remain on active duty after upper extremity amputations
Kift S, Bates T, Franklin N, Johnson A
US Army Med Dep J . 2017 Aug; (2-17):57-61. PMID: 28853121
Objectives: Return to duty following traumatic amputations has been extensively studied in those with lower extremity amputation. As upper extremity amputations occur less frequently, the issue of return to duty...
4.
CD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses
Dong H, Franklin N, Ritchea S, Yagita H, Glennie M, Bullock T
Eur J Immunol . 2015 Oct; 45(12):3289-301. PMID: 26461455
CD70-mediated stimulation of CD27 is an important cofactor of CD4(+) T-cell licensed dendritic cells (DCs). However, it is unclear how CD70-mediated stimulation of T cells is integrated with signals that...
5.
CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help
Dong H, Franklin N, Roberts D, Yagita H, Glennie M, Bullock T
J Immunol . 2012 Mar; 188(8):3829-38. PMID: 22422886
Fully functional CD8(+) T cell memory is highly dependent upon CD4(+) T cell support. CD4(+) T cells play a critical role in inducing the expression of CD70, the ligand for...
6.
Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells
Roberts D, Franklin N, Kingeter L, Yagita H, Tutt A, Glennie M, et al.
J Immunother . 2010 Sep; 33(8):769-79. PMID: 20842060
The immune response to the tumor can be enhanced by targeting costimulatory molecules on T cells. As the CD70-CD27 costimulatory axis plays an important role in the activation, survival, and...