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Timothy McDonald

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Articles 22
Citations 205
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Recent Articles
1.
Allesoe R, Lundgaard A, Hernandez Medina R, Aguayo-Orozco A, Johansen J, Nissen J, et al.
Nat Biotechnol . 2023 May; 41(7):1026. PMID: 37130959
No abstract available.
2.
Allesoe R, Lundgaard A, Hernandez Medina R, Aguayo-Orozco A, Johansen J, Nissen J, et al.
Nat Biotechnol . 2023 Jan; 41(3):399-408. PMID: 36593394
The application of multiple omics technologies in biomedical cohorts has the potential to reveal patient-level disease characteristics and individualized response to treatment. However, the scale and heterogeneous nature of multi-modal...
3.
Wesolowska-Andersen A, Brorsson C, Bizzotto R, Mari A, Tura A, Koivula R, et al.
Cell Rep Med . 2022 Feb; 3(1):100477. PMID: 35106505
The presentation and underlying pathophysiology of type 2 diabetes (T2D) is complex and heterogeneous. Recent studies attempted to stratify T2D into distinct subgroups using data-driven approaches, but their clinical utility...
4.
Lynam A, McDonald T, Hill A, Dennis J, Oram R, Pearson E, et al.
BMJ Open . 2019 Sep; 9(9):e031586. PMID: 31558459
Objective: To develop and validate multivariable clinical diagnostic models to assist distinguishing between type 1 and type 2 diabetes in adults aged 18-50. Design: Multivariable logistic regression analysis was used...
5.
Wang P, Zhang J, Feng J, Wang S, Guo L, Wang Y, et al.
Bioresour Technol . 2019 Mar; 281:217-225. PMID: 30822643
In the clostridial acetone-butanol-ethanol (ABE) fermentation, the intermediate acetate and butyrate are re-assimilated for solvent production. Here, key genes in ABE pathways in Clostridium saccharoperbutylacetonicum N1-4 were overexpressed to enhance...
6.
Davidson J, McDonald T, Sutherland C, Mostazir M, VanAalten L, Wilkin T
PLoS One . 2017 Apr; 12(4):e0171716. PMID: 28426711
Aims: Reference laboratories advise immediate separation and freezing of samples for the assay of proinsulin, which limit its practicability for smaller centres. Following the demonstration that insulin and C-peptide are...
7.
Pan P, McDonald T, Fulton J, Via B, Hung J
Sensors (Basel) . 2016 Dec; 17(1). PMID: 28025536
An 8-electrode capacitance tomography (ECT) sensor was built and used to measure moisture content (MC) and mass flow of pine chip flows. The device was capable of directly measuring total...
8.
Perry M, Bewshea C, Brown R, So K, Ahmad T, McDonald T
Ann Clin Biochem . 2015 Mar; 52(Pt 6):672-4. PMID: 25780249
Introduction: The biologic anti-tumour necrosis factor alpha (anti-TNFα) agents infliximab and adalimumab are monoclonal antibodies with binding specificity to TNFα, which are used for the treatment of Crohn's disease. Clinical...
9.
Mello M, Boothman R, McDonald T, Driver J, Lembitz A, Bouwmeester D, et al.
Health Aff (Millwood) . 2014 Jan; 33(1):20-9. PMID: 24395931
In communication-and-resolution programs (CRPs), health systems and liability insurers encourage the disclosure of unanticipated care outcomes to affected patients and proactively seek resolutions, including offering an apology, an explanation, and,...
10.
Sage W, Gallagher T, Armstrong S, Cohn J, McDonald T, Gale J, et al.
Health Aff (Millwood) . 2014 Jan; 33(1):11-9. PMID: 24395930
Communication-and-resolution programs (CRPs) in health care organizations seek to identify medical injuries promptly; ensure that they are disclosed to patients compassionately; pursue timely resolution through patient engagement, explanation, and, where...