Timothy M Curtis
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Explore the profile of Timothy M Curtis including associated specialties, affiliations and a list of published articles.
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15
Citations
709
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Recent Articles
1.
Wallace R, Rochfort K, Barabas P, Curtis T, Uehara H, Ambati B, et al.
Vascul Pharmacol
. 2021 Sep;
141:106919.
PMID: 34583025
The Angiopoietin-1/2 system is an opportune target for therapeutic intervention in a wide range of vascular pathologies, particularly through its association with endothelium. The complex multi-domain structure of native human...
2.
Llorian-Salvador M, Barabas P, Byrne E, Lechner J, Augustine J, Curtis T, et al.
Invest Ophthalmol Vis Sci
. 2020 Sep;
61(11):35.
PMID: 32945843
Purpose: Müller glia are important in retinal health and disease and are a major source of retinal VEGF-A. Of the different VEGF family members, the role of VEGF-A in retinal...
3.
Rochfort K, Carroll L, Barabas P, Curtis T, Ambati B, Barron N, et al.
Invest Ophthalmol Vis Sci
. 2019 Aug;
60(10):3547-3555.
PMID: 31415078
Purpose: Current treatments for diabetic retinopathy (DR) have considerable limitations, underpinning the need for new therapeutic options. In this article, the ability of an engineered angiopoietin-1 variant (COMP-Ang1) to ameliorate...
4.
Clarke R, Monaghan K, About I, Griffin C, Sergeant G, El Karim I, et al.
Eur Respir J
. 2017 Sep;
50(3).
PMID: 28931666
The cough reflex becomes hyperresponsive in acute and chronic respiratory diseases, but understanding the underlying mechanism is hampered by difficulty accessing human tissue containing both nerve endings and neuronal cell...
5.
El Karim I, McCrudden M, Linden G, Abdullah H, Curtis T, McGahon M, et al.
Am J Pathol
. 2015 Sep;
185(11):2994-3002.
PMID: 26358221
The transient receptor potential (TRP) channels are unique cellular sensors that are widely expressed in many neuronal and nonneuronal cells. Among the TRP family members, TRPA1 and TRPV4 are emerging...
6.
Stitt A, Curtis T, Chen M, Medina R, Mckay G, Jenkins A, et al.
Prog Retin Eye Res
. 2015 Aug;
51:156-86.
PMID: 26297071
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and remains a leading cause of vision loss globally. Its aetiology and pathology have been extensively studied for half...
7.
Cahoon J, Olson P, Nielson S, Miya T, Bankhead P, McGeown J, et al.
Exp Eye Res
. 2013 Dec;
120:15-9.
PMID: 24333760
Simultaneous non-invasive visualization of blood vessels and nerves in patients can be obtained in the eye. The retinal vasculature is a target of many retinopathies. Inflammation, readily manifest by leukocyte...
8.
Stitt A, Lois N, Medina R, Adamson P, Curtis T
Clin Sci (Lond)
. 2013 Mar;
125(1):1-17.
PMID: 23485060
Diabetic retinopathy remains the most common complication of diabetes mellitus and is a leading cause of visual loss in industrialized nations. The clinicopathology of the diabetic retina has been extensively...
9.
Zholos A, Curtis T
Curr Top Med Chem
. 2013 Feb;
13(3):295-309.
PMID: 23432062
In recent years, research on the roles of TRP channels in vascular function and disease has undergone a rapid expansion from tens of reports published in the early 2000s to...
10.
Stitt A, Curtis T
J Ocul Biol Dis Infor
. 2012 Dec;
4(1-2):10-8.
PMID: 23272270
The pathogenesis of diabetic retinopathy is complex, reflecting the array of systemic and tissue-specific metabolic abnormalities. A range of pathogenic pathways are directly linked to hyperglycaemia and dyslipidaemia, and the...